Evaluation of the Oxo-bridged Dinuclear Ruthenium Ammine Complex as Redox Mediator in an Electrochemical Biosensor

Author(s)

Raymundo-Pereira, Paulo A. ^{[1, 2]} ; Mascarenhas, Ana C. V. ^[1] ; Teixeira, Marcos F. S. ^[1]

Affiliation

^[1] Sao Paulo State Univ, UNESP, Fac Sci & Technol, Rua Roberto Simonsen 305, BR-19060900 Presidente Prudente, SP - Brazil

^[2] Univ Sao Paulo, Sao Carlos Inst Chem, CP 380, BR-13566590 Sao Carlos, SP - Brazil

• Document type: Journal article
• Source: Electroanalysis; v. 28, n. 3, p. 562-569, MAR 2016.
• Web of Science Citations: 2

Abstract

The mediation of electron-transfer by oxo-bridged dinuclear ruthenium ammine {[}(bpy)(2)(NH3)Ru-III(mu-O)Ru-III(NH3)(bpy)(2)](4+) for the oxidation of glucose was investigated by cyclic voltammetry. These ruthenium (III) complexes exhibit appropriate redox potentials of 0.131-0.09V vs. SCE to act as electron-transfer mediators. The plot of anodic current vs. the glucose concentration was linear in the concentration range between 2.52x10(-5) and 1.00x10(-4)molL(-1). Moreover, the apparent Michaelis-Menten kinetic (K-M(app)) and the catalytic (K-cat) constants were 8.757x10(-6)molL(-1) and 1,956s(-1), respectively, demonstrating the efficiency of the ruthenium dinuclear oxo-complex {[}(bpy)(2)(NH3)Ru-III(mu-O)Ru-III(NH3)(bpy)(2)](4+) as mediator of redox electron-transfer. (AU)

• FAPESP's process: 12/17689-9 - Preparation and characterization of bifunctional-nanostructured surfaces of Au-Pt obtained via templates for application in sensors and biosensors
• Grantee: Paulo Augusto Raymundo Pereira
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 08/07298-7 - Study of polymeric films of thiophene-Schiff base complexes in the construction of electrochemical sensors
• Grantee: Paulo Augusto Raymundo Pereira
• Support Opportunities: Scholarships in Brazil - Master