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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Production of virulence factors in Candida strains isolated from patients with denture stomatitis and control individuals

Full text
Author(s):
Pereira, Cristiane Aparecida [1] ; Domingues, Nadia [1] ; Santos Alves Araujo, Maria Izabel Daniel [1] ; Junqueira, Juliana Campos [1] ; Back-Brito, Graziella Nuernberg [1] ; Cardoso Jorge, Antonio Olavo [1]
Total Authors: 6
Affiliation:
[1] UNESP Univ Estadual Paulista, Inst Sci & Technol, Francisco Jose Longo 777, BR-12245000 Sao Jose Dos Compos, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE; v. 85, n. 1, p. 66-72, MAY 2016.
Web of Science Citations: 4
Abstract

The aim of this study was to evaluate the production of virulence factors in Candida isolates from the oral cavities of 50 patients with different degrees of denture stomatitis (DS, type I, II and III) and 50 individuals without signs of DS. We evaluated the enzymatic and hemolytic activities, the biofilm formation, and the cell surface hydrophobicity (CSH) in all isolates. Germ tube (GT) production was also evaluated in Candida albicans and Candida dubliniensis isolates. In C. albicans and C. dubliniensis the secretion of hemolysin and GT production was significantly different between isolates from patients with DS and individuals without DS. No significant difference was observed in the production of virulence factors by Candida glabrata isolates. Candida isolates expressed a wide range of virulence factors. However, in the majority of isolates from the type III lesions, the production of the virulence factors was higher than for the other groups. (C) 2016 Elsevier Inc. All rights reserved. (AU)

FAPESP's process: 10/00879-4 - OPPORTUNISTIC MICROORGANISMS IN INJURIES denture stomatitis AND INFLUENCE OF PHOTODYNAMIC THERAPY IN VIRULENCE FACTORS OF Candida spp.
Grantee:Cristiane Aparecida Pereira Correia
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 13/07411-6 - Polymicrobial biofilms: study, characterization, evaluation of pathogenicity in Galleria mellonella, and influence in the expression of C. albicans virulence genes.
Grantee:Cristiane Aparecida Pereira Correia
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 10/08936-7 - OPPORTUNISTIC MICROORGANISMS IN INJURIES denture stomatitis AND INFLUENCE OF PHOTODYNAMIC THERAPY IN VIRULENCE FACTORS OF Candida spp.
Grantee:Antonio Olavo Cardoso Jorge
Support Opportunities: Regular Research Grants