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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

New Small Plasmid Harboring bla(KPC-2) in Pseudomonas aeruginosa

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Galetti, Renata [1] ; Andrade, Leonardo Neves [1] ; Chandler, Michael [2] ; Varani, Alessandro de Mello [3] ; Costa Darini, Ana Lucia [1]
Total Authors: 5
[1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, BR-14049 Ribeirao Preto - Brazil
[2] CNRS, Lab Microbiol & Genet Mol, Toulouse - France
[3] Univ Estadual Paulista, Fac Ciencias Agr & Vet, Jaboticabal - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Antimicrobial Agents and Chemotherapy; v. 60, n. 5, p. 3211-3214, MAY 2016.
Web of Science Citations: 4

The aim of this study was to characterize the genetic context of bla(KPC-2) in Pseudomonas aeruginosa sequence type 244 from Brazil. The bla(KPC-2) gene was detected in a new small plasmid, pBH6. Complete sequencing revealed that pBH6 was 3,652 bp long and included the Tn3 resolvase and Tn3 inverted repeat (IR), a partial copy of ISKpn6, and a putative ori region but no rep genes. pBH6 replicated stably into Escherichia coli strain DH10B and P. aeruginosa strain PAO. (AU)

FAPESP's process: 14/14494-8 - Molecular epidemiology of gram-negative bacteria and genetic of antibiotic resistance
Grantee:Ana Lúcia da Costa Darini
Support type: Research Projects - Thematic Grants