Frequency of anti-Toxoplasma gondii IgA, IgM, and IgG antibodies in high-risk pregnancies, in Brazil

Author(s)

Antunes Murata, Fernando Henrique ; Ferreira, Marina Neves ; Camargo, Natalia Sahyoun ; Santos, Gabriela Soria ; Junqueira Franco Spegiorin, Ligia Cosentino ; Silveira-Carvalho, Aparecida Perpetuo ; Pereira-Chioccola, Vera Lucia ; de Mattos, Luiz Carlos ; Brandao de Mattos, Cinara Cassia

• Document type: Journal article
• Source: Revista da Sociedade Brasileira de Medicina Tropical; v. 49, n. 4, p. 512-514, JUL-AUG 2016.
• Web of Science Citations: 3

Abstract

Introduction: Toxoplasmosis during pregnancy can be severe; thus, it is essential to diagnose the disease via serological tests. Methods: An enzyme-linked immunosorbent assay (ELISA) was used to investigate anti-Toxoplasma gondii immunoglobulin A (IgA), M (IgM) and G (IgG) antibodies in 62 high-risk pregnant women. Results: Forty-three (69.4%) women were positive for IgA, 31 (50%) for IgG, and 57 (91.9%) for IgM; 4 (6,5%) were positive for IgA but negative for IgM; 10 (16.1%) were negative for IgA and IgM but positive for IgG. Conclusions: Testing for these antibodies can help diagnose infection in pregnant women, thereby contributing to clinical management. (AU)

• FAPESP's process: 12/07716-9 - Serological and molecular investigation of Toxoplasma gondii in blood donors
• Grantee: Luiz Carlos de Mattos
• Support Opportunities: Regular Research Grants
• FAPESP's process: 13/15879-8 - Toxoplasma gondii infection: serological and molecular characterization in patients attended in public health service (SUS)
• Grantee: Fernando Henrique Antunes Murata
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 14/01706-7 - Genotypic characterization of Toxoplasma gondii in samples of pregnant women in the northwest region of the state of São Paulo
• Grantee: Marina Neves Ferreira
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 14/09496-1 - New diagnostic strategies employed in symptomatic toxoplasmosis
• Grantee: Vera Lúcia Pereira Chioccola
• Support Opportunities: Regular Research Grants