| Full text | |
| Author(s): Show less - |
Fernandes, Miriam R.
;
McCulloch, John A.
;
Vianello, Marco A.
;
Moura, Quezia
;
Perez-Chaparro, Paula J.
;
Esposito, Fernanda
;
Sartori, Luciana
;
Dropa, Milena
;
Matte, Maria H.
;
Lira, Debora P. A.
;
Mamizuka, Elsa M.
;
Lincopan, Nilton
Total Authors: 12
|
| Document type: | Journal article |
| Source: | Antimicrobial Agents and Chemotherapy; v. 60, n. 10, p. 6415-6417, OCT 2016. |
| Web of Science Citations: | 57 |
| Abstract | |
A colistin-resistant Escherichia coli strain was recovered from a patient with a diabetic foot infection in Brazil. Whole-genome analysis revealed that the E. coli isolate belonged to the widespread sequence type (ST) 101 and harbored the mcr-1 gene on an IncX4 plasmid that was highly similar to mcr-1-bearing IncX4 plasmids that were recently identified in Enterobacteriaceae from food, animal, and human samples recovered on different continents. These results suggest that self-transmissible IncX4-type plasmids may represent promiscuous plasmids contributing to the intercontinental spread of the mcr-1 gene. (AU) | |
| FAPESP's process: | 13/12107-4 - Study of the heterogeneous resistance to vancomycin in Staphylococcus aureus by comparative single-cell genomics of subpopulations in a single isolate |
| Grantee: | John Anthony McCulloch |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |