| Full text | |
| Author(s): |
Morocho-Jacome, Ana Lucia
;
Sato, Sunao
;
Capurro Guimaraes, Lais de Lara
;
Camargo de Jesus, Camila Knysak
;
Monteiro de Carvalho, Joao Carlos
Total Authors: 5
|
| Document type: | Journal article |
| Source: | ENGINEERING IN LIFE SCIENCES; v. 16, n. 4, p. 338-347, MAY 2016. |
| Web of Science Citations: | 0 |
| Abstract | |
Arthrospira platensis is widely cultivated in open ponds for industrial purposes. However, high-protein A. platensis biomass produced in photobioreactors (PBRs) is recommended for pharmaceutical and cosmetic formulations. A. platensis was cultivated in a 3.5 L tubular airlift PBR using both sodium nitrate and urea as nitrogen sources. Sodium nitrate was added from the start of the cultivation using a batch process. Urea was supplied daily at exponentially increasing feeding rate using a fed-batch process. The simultaneous optimization of the independent variables, namely, total quantity of sodium nitrate (m(T1)) and total quantity of urea (m(T2)), led to an optimal condition of m(T1) = 15.0 mmol/L and m(T2) = 7.5 mmol/L. Maximum biomass concentration (5183 +/- 94 mg/L) corresponding to the highest biomass productivity (683 +/- 13 mg/L/day) was obtained under such condition. The addition protocol of both nitrogen sources resulted in high productivities of protein (6.2 +/- 0.4 mg/L/day) as well as chlorophyll-a (372.2 +/- 7.7 mg/L/day). Such innovative process could be applied in the large-scale production of A. platensis using tubular PBR for novel applications. (AU) | |
| FAPESP's process: | 11/52028-0 - Reuse of the culture medium of Arthrospira platensis using physical-chemical treatments |
| Grantee: | João Carlos Monteiro de Carvalho |
| Support Opportunities: | Regular Research Grants |