Maternal and fetal outcomes in pregnancies complicated by overweight and obesity

Author(s)

Vernini, Joice Monaliza ; Moreli, Jusciele Brogin ; Magalhaes, Claudia Garcia ; Araujo Costa, Roberto Antonio ; Cunha Rudge, Marilza Vieira ; Paranhos Calderon, Iracema Mattos

• Document type: Journal article
• Source: Reproductive Health; v. 13, AUG 27 2016.
• Web of Science Citations: 7

Abstract

Background: Overweight and obesity are associated with pregnancy complications and adverse perinatal outcomes, posing short and long-term risks for maternal and child health. This study evaluated maternal, delivery and neonatal outcomes in pregnancies complicated by overweight and obesity. Methods: This prospective cross-sectional study included 258 pregnant women. According to prepregnancy body mass index (BMI), participants were classified as normal weight, overweight, or obese. Data were analyzed using the chi-square test and analysis of variance followed by the Tukey test. Logistic regression was performed to calculate odds ratios and 95 % confidence intervals (p < 0.05). Results: Most women >= 35 years old were overweight (22.7 %) and obese (27.6 %). Prepregnancy diabetes was significantly associated with obesity (15.7 %, p < 0.000). Obese women showed the lowest weight gain (9.6 +/- 7.5Kg). Overweight and obese women practiced physical exercise more frequently (p = 0.010) than normal weight women. A greater proportion of obese mothers (13.4 %) had large for gestational age babies (p = 0.021), with higher thoracic circumference (33.6 +/- 2.0 cm) and abdominal circumference (31.6 +/- 2.3 cm). Obesity increased the risk of developing hypertension (OR = 7.0; 3.1-15.9), hyperglycemic disturbances (OR = 5.5; 2.9-10.6) and HbA1c >= 6. 5 % (OR = 3.7; 1.2-11.1). The infants born to obese mothers had longer hospital stay (3.9 +/- 3.9 days) (p = 0.005). Conclusion: Our results confirm that obesity in pregnancy can lead to adverse outcomes, and underscore the importance of identifying and treating inadequate weight status during pregnancy. (AU)

• FAPESP's process: 12/51257-9 - Investigation on new risk factors and on quality of life related to diabetes or hyperglycemia diagnosis in pregnancy
• Grantee: Iracema de Mattos Paranhos Calderon
• Support Opportunities: Research Grants - Research in Public Policies for the National Health Care System (PP-SUS)