Advanced search
Start date
Betweenand
Related content
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The transovarial transmission in the dynamics of dengue infection: Epidemiological implications and thresholds

Full text
Author(s):
Yang, Hyun Mo
Total Authors: 1
Document type: Journal article
Source: MATHEMATICAL BIOSCIENCES; v. 286, p. 1-15, APR 2017.
Web of Science Citations: 4
Abstract

The anthropophilic and peridomestic female mosquito Aedes aegypti bites humans to suck blood to maturate fertilized eggs, during which dengue virus can be spread between mosquito and human populations. Besides this route of transmission, there is a possibility of dengue virus being passed directly to offspring through transovarial (or vertical) transmission. The effects of both horizontal and transovarial transmission routes on the dengue virus transmission are assessed by mathematical modeling. From the model, the reproduction number is obtained and the contribution of transovarial transmission is evaluated for different levels of horizontal transmission. Notably, the transovarial transmission plays an important role in dengue spread when the reproduction number is near one. Another threshold parameter arises, which is the product of the fractions of the susceptible populations of humans and mosquitoes. Interestingly, these two threshold parameters can be obtained from three different approaches: the spectral radius of the next generation matrix, the Routh-Hurwitz criteria and M-matrix theory. (C) 2017 Elsevier Inc. All rights reserved. (AU)

FAPESP's process: 09/15098-0 - Assessing control of epidemics using mathematical and computer models
Grantee:Hyun Mo Yang
Support Opportunities: Research Projects - Thematic Grants