Long-term interdisciplinary therapy decreases symptoms of binge eating disorder and prevalence of metabolic syndrome in adults with obesity

Author(s)

Leite, Paula Bresciani ; Damaso, Ana Raimunda ; Poli, Vanessa Schoenardie ; Sanches, Ricardo Badan ; Andrade Silva, Stephan Garcia ; Novo Fidalgo, Joao Pedro ; Nascimento, Maythe Amaral ; Machado de Oliveira, Camila Aparecida ; Caranti, Danielle Arisa

• Document type: Journal article
• Source: Nutrition Research; v. 40, p. 57-64, APR 2017.
• Web of Science Citations: 2

Abstract

Obesity-associated comorbidities greatly impact the quality and expectancy of life. Binge eating disorder (BED) is the most prevalent eating disorder and it is an important risk factor for obesity and metabolic syndrome (MetS). For these reasons, we aimed to assess the effect of an interdisciplinary therapy on the symptoms of BED and the prevalence of MetS in obese adults. It was hypothesized that the interdisciplinary therapy would decrease symptoms of BED and markers of MetS. Twenty-four volunteers (BMI 34.80 +/- 3.17 kg/m(2); 41.21 +/- 6.28 years old) completed a 32-week intervention. Biochemical characteristics, body composition, the degree of symptoms of binge eating, and macronutrients, and sodium consumption pre- and post-treatment were determined. The prevalence of MetS dropped from 75% to 45.8%, post-therapy. Among the markers of MetS, waist circumference and systolic blood pressure decreased significantly, whereas high-density lipoprotein levels increased. Fasting plasma glucose, diastolic blood pressure, and triglycerides did not change. Based on binge-eating scale (BES) scores, before therapy, 33.3% of volunteers were classified as moderate bingers, and after therapy all volunteers were classified as having no BED symptoms. No difference in the prevalence of MetS between individuals classified as normal or moderate bingers was observed, but we found a positive post-therapy correlation between the BES score and body fat, gynoid fat and trunk fat. Sodium, fat, and carbohydrate consumption decreased. Protein intake did not change. In conclusion, the interdisciplinary approach was efficient in reducing symptoms of BED and MetS prevalence in this population. (C) 2017 Elsevier Inc. All rights reserved. (AU)

• FAPESP's process: 11/51723-7 - Effects of interdisciplinary therapy on metabolic syndrome control in obese adults and its relationship with pro and anti inflammatory adipocytes
• Grantee: Danielle Arisa Caranti
• Support Opportunities: Regular Research Grants