Using. Metagenomics to Connect Microbial Community Biodiversity and Functions

Author(s)

Mendes, Lucas W. ; Perez Braga, Lucas Palma ; Navarrete, Acacio A. ; de Souza, Dennis Goss ; Silva, Genivaldo G. Z. ; Tsai, Siu M.

• Document type: Review article
• Source: CURRENT ISSUES IN MOLECULAR BIOLOGY; v. 24, p. 103-118, 2017.
• Web of Science Citations: 0

Abstract

Microbes constitute about a third of the Earth's biomass and are composed by an enormous genetic diversity. In a majority of environments the microbial communities play crucial roles for the ecosystem functioning, where a drastic biodiversity alteration or loss could lead to negative effects on the environment and sustainability. A central goal in microbiome studies is to elucidate the relation between microbial diversity to functions. A better understanding of the relation diversity-function would increase the ability to manipulate that diversity to improve plant and animal health and also setting conservation priorities. The recent advances in genomic methodologies in microbial ecology have provided means to assess highly complex communities in detail, making possible the link between diversity and the functions performed by the microbes. In this work we first explore some advances in bioinformatics tools to connect the microbial community biodiversity to their potential metabolism and after present some examples of how this information can be useful for a better understanding of the microbial role in the environment. (AU)

• FAPESP's process: 15/00251-9 - Analysis of the microbiome associated to the common bean root system
• Grantee: Lucas William Mendes
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
• FAPESP's process: 13/22845-2 - Interactions between sugarcane soil microbiota and earthworms on straw decomposition and emissions of greenhouse gases (GHG)
• Grantee: Lucas Palma Perez Braga
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 12/13321-7 - Taxonomic and functional microbial bio-indicators in soil under sugarcane biomass production systems
• Grantee: Acacio Aparecido Navarrete
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 10/20353-7 - Analysis of microbial communities in soils under different land uses on the frontier of agricultural expansion in Southwestern Amazonia
• Grantee: Lucas William Mendes
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 11/51749-6 - Functional bioindicators for soil quality monitoring for sustainable management of sugarcane biomass production (BIOSQ)
• Grantee: Tsai Siu Mui
• Support Opportunities: Program for Research on Bioenergy (BIOEN) - Regular Program Grants
• FAPESP's process: 14/03217-3 - Rhizosphere microbiome of common bean resistant to the soil pathogen Fusarium oxysporum
• Grantee: Lucas William Mendes
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 14/06077-8 - Metagenomic annotation and bioinformatics analysis applied to definition of microbial bioindicators for soil agricultural management effects in sugarcane production systems
• Grantee: Acacio Aparecido Navarrete
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor