Quantification of bleeding during dental extraction in patients on dual antiplatelet therapy

Author(s)

Buhatem Medeiros, F. ; Pepe Medeiros de Rezende, N. ; Bertoldi Franco, J. ; Porrio de Andrade, A. C. ; Timerman, L. ; Gallottini, M. ; Itagiba Neves, I. L. ; Ortega, K. L.

• Document type: Journal article
• Source: International Journal of Oral and Maxillofacial Surgery; v. 46, n. 9, p. 1151-1157, SEP 2017.
• Web of Science Citations: 5

Abstract

In spite of the possibility of triggering thromboembolic events, many professionals indicate the suspension of antiplatelet agents before dental surgical procedures. The aim of this study was to perform a quantitative assessment of intraoperative bleeding in patients on dual antiplatelet therapy. A case control study was conducted in patients on dual antiplatelet therapy (APT group) and in patients who did not use these medications (control group). The following examinations were requested: complete blood cell count, blood coagulation tests, and platelet aggregation. The quantity of bleeding was measured intraoperatively by collection of aspirated blood. The mean volume of blood lost during the surgical procedure was 6.10 ml in the control group and 16.07 ml in the APT group (P = 0.002). The mean volume of blood lost per minute was 0.60 ml/min in the control group and 1 ml/min in the APT group (P = 0.001), with local haemostatic methods being sufficient to control the bleeding. There was no postoperative bleeding complication in any case. Patients on dual antiplatelet therapy presented a larger volume of bleeding, but this could be controlled by means of local haemostatic measures. Therefore, there is no need to stop either of the two dual antiplatelet therapy medications before dental extractions. (AU)

• FAPESP's process: 12/16523-0 - Tooth extraction in patients with coronary artery disease in dual antiplatelet therapy: a prospective randomized study
• Grantee: Karem López Ortega
• Support Opportunities: Regular Research Grants