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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Interactions between sleep, stress, and metabolism: From physiological to pathological conditions

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Hirotsu, Camila ; Tufik, Sergio ; Andersen, Monica Levy
Total Authors: 3
Document type: Review article
Source: SLEEP SCIENCE; v. 8, n. 3, p. 143-152, NOV 2015.
Web of Science Citations: 45

Poor sleep quality due to sleep disorders and sleep loss is highly prevalent in the modern society. Underlying mechanisms show that stress is involved in the relationship between sleep and metabolism through hypothalamicpituitaryadrenal (HPA) axis activation. Sleep deprivation and sleep disorders are associated with maladaptive changes in the HPA axis, leading to neuroendocrine dysregulation. Excess of glucocorticoids increase glucose and insulin and decrease adiponectin levels. Thus, this review provides overall view of the relationship between sleep, stress, and metabolism from basic physiology to pathological conditions, highlighting effective treatments for metabolic disturbances. (C) 2015 Brazilian Associationof Sleep. Production and Hosting by Elsevier B.V. (AU)

FAPESP's process: 14/15259-2 - Epidemiology of sleep in the city of São Paulo: follow-up of volunteers from the population-based study EPISONO
Grantee:Camila Hirotsu
Support type: Scholarships in Brazil - Post-Doctorate