| Full text | |
| Author(s): |
Hirotsu, Camila
;
Tufik, Sergio
;
Andersen, Monica Levy
Total Authors: 3
|
| Document type: | Review article |
| Source: | SLEEP SCIENCE; v. 8, n. 3, p. 143-152, NOV 2015. |
| Web of Science Citations: | 45 |
| Abstract | |
Poor sleep quality due to sleep disorders and sleep loss is highly prevalent in the modern society. Underlying mechanisms show that stress is involved in the relationship between sleep and metabolism through hypothalamicpituitaryadrenal (HPA) axis activation. Sleep deprivation and sleep disorders are associated with maladaptive changes in the HPA axis, leading to neuroendocrine dysregulation. Excess of glucocorticoids increase glucose and insulin and decrease adiponectin levels. Thus, this review provides overall view of the relationship between sleep, stress, and metabolism from basic physiology to pathological conditions, highlighting effective treatments for metabolic disturbances. (C) 2015 Brazilian Associationof Sleep. Production and Hosting by Elsevier B.V. (AU) | |
| FAPESP's process: | 14/15259-2 - Epidemiology of sleep in the city of São Paulo: follow-up of volunteers from the population-based study EPISONO |
| Grantee: | Camila Hirotsu |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |