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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Genomic characterization and evolution of Tacaiuma orthobunyavirus (Peribunyaviridae family) isolated in Brazil

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de Melo Junior, Aristides Bezerra [1] ; de Souza, William Marciel [2] ; Acrani, Gustavo Olszanski [3] ; Carvalho, Valeria Lima [1] ; Romeiro, Marilia Farignoli [2] ; Tolardo, Aline Lavado [2] ; da Silva, Sandro Patroca [4] ; Cardoso, Jedson Ferreira [4] ; Chiang, Jannifer de Oliveira [1] ; da Silva Goncalves Vianez Junior, Joao Lidio [4] ; da Silva Azevedo, Raimunda do Socorro [1] ; Moraes Figueiredo, Luiz Tadeu [2] ; da Costa Vasconcelos, Pedro Fernando [1] ; Teixeira Nunes, Marcio Roberto [4] ; de Almeida Medeiros, Daniele Barbosa [1]
Total Authors: 15
[1] Minist Hlth, Evandro Chagas Inst, Dept Arbovirol & Hemorrhag Fevers, Ananindeua, Para - Brazil
[2] Univ Sao Paulo, Sch Med Ribeirao Preto, Virol Res Ctr, Ribeirao Preto, SP - Brazil
[3] Univ Fed Fronteira Sul, Passo Fundo, RS - Brazil
[4] Minist Hlth, Evandro Chagas Inst, Ctr Technol Innovat, Ananindeua, Para - Brazil
Total Affiliations: 4
Document type: Journal article
Source: INFECTION GENETICS AND EVOLUTION; v. 60, p. 71-76, JUN 2018.
Web of Science Citations: 0

Tacaiuma virus (TCMV) is antigenically characterized as a member of the Anopheles A complex in the Orthobunyavirus genus, Peribunyaviridae family (Bunyavirales order). Clinically, the TCMV infection is characterized by acute febrile illness with myalgia and arthralgia lasting three to five days. However, the genomic and evolutionary aspect of this virus has not been elucidated. In this study, we described the complete coding sequences of three segments of two TCMV strains isolated in Brazil and three complete coding sequences of the small segment of three TCMV strains. All the strains sequenced in this study showed the typical genomic organization of orthobunyaviruses that infect vertebrates, except for the absence of the open reading frame that encodes the well-described non-structural small protein. This study presents the genomic and evolutionary characterization of TCMV strains and would be helpful for diagnostic purposes and epidemiology. (AU)

FAPESP's process: 12/24150-9 - Research of virus in wild rodents, mosquitoes and ticks
Grantee:William Marciel de Souza
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 17/13981-0 - Characterization, genomics and diagnostic of viruses with importance for public health in Brazil by high throughput sequencing
Grantee:William Marciel de Souza
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 14/02438-6 - Studies with Bunyaviridae that produce human disease
Grantee:Luiz Tadeu Moraes Figueiredo
Support type: Research Projects - Thematic Grants
FAPESP's process: 14/20851-8 - Study about Alphavirus and Flavivirus infections in samples of blood bank
Grantee:Marilia Farignoli Romeiro
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 16/17457-1 - Compounds screening with potential antiviral action against alphaviruses and orthobunyaviruses
Grantee:Aline Lavado Tolardo
Support type: Scholarships in Brazil - Doctorate