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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Carotid intima-media thickness in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil): a narrative review

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Author(s):
Sena Santos, Eduardo Henrique [1, 2, 3] ; dos Santos Neto, Pedro Jose [1, 2, 3] ; Santos, Itamar de Souza [1, 2, 4]
Total Authors: 3
Affiliation:
[1] Univ Sao Paulo, HU, Sao Paulo, SP - Brazil
[2] Univ Sao Paulo, HU, Ctr Clin & Epidemiol Res, Sao Paulo, SP - Brazil
[3] Univ Sao Paulo, HU, Imaging Serv, Sao Paulo, SP - Brazil
[4] Univ Sao Paulo FMUSP, Fac Med, Dept Internal Med, Sao Paulo, SP - Brazil
Total Affiliations: 4
Document type: Journal article
Source: São Paulo Medical Journal; v. 136, n. 1, p. 64-72, JAN-FEB 2018.
Web of Science Citations: 3
Abstract

ABSTRACT BACKGROUND: Carotid intima-media thickness (CIMT), as measured by ultrasound, has been used in large studies as a non-invasive marker for subclinical atherosclerosis. The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) is a cohort of 15,105 civil servants in six Brazilian cities that included CIMT evaluation in its baseline assessment. The aim of the present narrative review was to provide an overview of ELSA-Brasil CIMT articles published up to July 31, 2017. DESIGN AND SETTING: Narrative review of ELSA-Brasil CIMT studies using baseline assessment data. METHODS: We searched PubMed for the terms “ELSA-Brasil” and “intima-media”. This search yielded 21 published articles using CIMT data from the ELSA-Brasil baseline assessment, which were included in this review. We also present information about intima-media thickness assessment from ongoing onsite reevaluations of the study participants. RESULTS: Most published studies focused on the association with traditional and novel cardiovascular risk factors. Studies also presented information about the ELSA-Brasil CIMT protocol at baseline and CIMT value distribution in this large sample. CONCLUSIONS: Analyses on the ELSA-Brasil data led to important insights on CIMT interpretation and physiology. Besides the highlighted contributions which have already been made in this field, new data gathered during the ongoing third onsite assessment will enable investigation of substantially new research questions. (AU)

FAPESP's process: 15/17013-3 - Prevalence, incidence and recovery from anemia and its causes, and the association with cognitive performance in the ELSA-Brasil cohort
Grantee:Itamar de Souza Santos
Support Opportunities: Regular Research Grants