Vaccinia Virus in Blood Samples of Humans, Domestic and Wild Mammals in Brazil

Author(s):Show less -

Peres, Marina G. ^[1] ; Bacchiega, Thais S. ^[1] ; Appolinario, Camila M. ^[1] ; Vicente, Acacia F. ^[1] ; Ribeiro Mioni, Mateus de Souza ^[1] ; Ribeiro, Bruna L. D. ^[1] ; Fonseca, Clovis R. S. ^[1] ; Pelicia, Vanessa C. ^[1] ; Ferreira, Fernando ^[2] ; Oliveira, Graziele P. ^[3] ; Abrahao, Jonatas S. ^[3] ; Megid, Jane ^[1]

Affiliation

^[1] UNESP Univ Estadual Paulista, Fac Med Vet & Zootecnia, BR-18618970 Botucatu, SP - Brazil

^[2] Univ Sao Paulo, Fac Med Vet & Zootecnia, BR-05508270 Sao Paulo - Brazil

^[3] Univ Fed Minas Gerais, Inst Ciencias Biol, BR-31270901 Belo Horizonte, MG - Brazil

• Document type: Journal article
• Source: Viruses-Basel; v. 10, n. 1 JAN 2018.
• Web of Science Citations: 0

Abstract

Outbreaks of Vaccinia virus (VACV) affecting cattle and humans have been reported in Brazil in the last 15 years, but the origin of outbreaks remains unknown. Although VACV DNA have been already detected in mice (Mus musculus), opossums (Didelphis albiventris) and dogs during VACV zoonotic outbreaks, no transmission to cattle or humans from any of these were reported during Brazilian outbreaks. In this work, we assessed the PCR positivity to VACV in blood samples of cows and other domestic mammals, wild rodents and other wild mammals, and humans from areas with or without VACV infection reports. Our results show the detection of VACV DNA in blood samples of cows, horse and opossums, raising important questions about VACV spread. (AU)

• FAPESP's process: 13/07693-1 - Phylogenetic analysis of the Vaccinia virus (VACV) circulating in wild and domestic animals of the Central West region of São Paulo State
• Grantee: Marina Gea Peres Serafim
• Support Opportunities: Scholarships in Brazil - Doctorate