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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Multi-isotope calibration for inductively coupled plasma mass spectrometry

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Author(s):
Virgilio, Alex [1] ; Nobrega, Joaquim A. [1] ; Donati, George L. [2]
Total Authors: 3
Affiliation:
[1] Univ Fed Sao Carlos, Dept Chem, Grp Appl Instrumental Anal, POB 676, BR-13565905 Sao Paulo - Brazil
[2] Wake Forest Univ, Dept Chem, Salem Hall, POB 7486, Winston Salem, NC 27109 - USA
Total Affiliations: 2
Document type: Journal article
Source: ANALYTICAL AND BIOANALYTICAL CHEMISTRY; v. 410, n. 3, p. 1157-1162, JAN 2018.
Web of Science Citations: 13
Abstract

Multi-isotope calibration (MICal) is a novel approach to calibration for inductively coupled plasma mass spectrometry (ICP-MS). In MICal, only two calibration solutions are required: solution A, composed of 50% v v(-1) of sample and 50% v v(-1) of a standard solution containing the analytes, and solution B, composed of 50% v v(-1) of sample and 50% v v(-1) of a blank solution. MICal is based on monitoring the signal intensities of several isotopes of the same analyte in solutions A and B. By plotting the analytical signals from solution A in the x-axis, and from solution B in the y-axis, the analyte concentration in the sample is calculated using the slope of that graph and the concentration of the reference standard added to solution A. As both solutions contain the same amount of sample, matrix-matching is easily achieved. In this proof-of-concept study, MICal was applied to the determination of Ba, Cd, Se, Sn, and Zn in seven certified reference materials with different matrices (e.g., plant materials, flours, and water). In most cases, MICal results presented no statistical difference from the certified values at a 95% confidence level. The new strategy was also compared with traditional calibration methods such as external calibration, internal standardization and standard additions, and recoveries were generally better for MICal. This is a simple, accurate, and fast alternative method for matrix-matching calibration in ICP-MS. (AU)

FAPESP's process: 14/18393-1 - Evaluation of gradient flow analysis as calibration strategy for spectroanalytical techniques with plasma source
Grantee:Alex Virgilio
Support Opportunities: Scholarships in Brazil - Post-Doctoral