Advanced search
Start date
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Kavalactones and Benzoic Acid Derivatives from Leaves of & IT;Piper & IT; & IT;fuligineum & IT; Kunth (Piperaceae)

Full text
Mazzeu, Bruna F. [1] ; Felippe, Lidiane G. [1] ; Cotinguiba, Fernando [2] ; Kato, Massuo J. [3] ; Furlan, Maysa [1]
Total Authors: 5
[1] Univ Estadual Paulista Unesp, Inst Quim, CP 355, BR-14800900 Araraquara, SP - Brazil
[2] Univ Fed Rio de Janeiro, IPPN, BR-21941902 Rio De Janeiro, RJ - Brazil
[3] Univ Sao Paulo, Inst Quim, BR-05508000 Sao Paulo, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Journal of the Brazilian Chemical Society; v. 29, n. 6, p. 1286-1290, JUN 2018.
Web of Science Citations: 0

The known kavalactones (E)-4-methoxy-6-styryl-2H-pyran-2-one. 4-methoxy-6-(3-phenyloxiran-2-yl)-2H-pyran-2-one. 6-(1,2-dihydroxy-2-phenylethyl)-4-methoxy-2H-pyran-2-one, the three benzoic acid derivatives methyl-4-methoxy-3-(3'-methyl-2'-butenyl)benzoate and methyl 2,2-dimethyl-4-oxochroman-6-carboxylate, and a new methyl 4-methoxy-3-(3-methylbut-2-enoyl)benzoate were isolated from the ethanolic extract of Piper fuligineum. The structures of these compounds were determined by using a combination of spectroscopic methods, including 1D-and 2D-nuclear magnetic resonance spectroscopy and high-resolution mass spectrometry. This is the first report of the chemical study of P. fuligineum, and the methyl 4-methoxy-3-(3-methylbut-2-enoyl)benzoate is described as a new natural product. (AU)

FAPESP's process: 13/07600-3 - CIBFar - Center for Innovation in Biodiversity and Drug Discovery
Grantee:Glaucius Oliva
Support type: Research Grants - Research, Innovation and Dissemination Centers - RIDC
FAPESP's process: 14/50316-7 - Dimensions US-Biota São Paulo: Chemically mediated multi-trophic interaction diversity across tropical gradients
Grantee:Massuo Jorge Kato
Support type: BIOTA-FAPESP Program - Thematic Grants
FAPESP's process: 11/16752-6 - Study on the structural and biosynthetic Piper Fuligineum Kunth (Piperaceae)
Grantee:Bruna Fonseca Mazzeu
Support type: Scholarships in Brazil - Master
FAPESP's process: 13/15306-8 - Studies concerning the biosynthesis of quinonemethides triterpenes by metabolic engineering: evaluation of the micro- and macromolecular metabolic flow of heterologous system by proteomics and metabolomics techniques.
Grantee:Lidiane Gaspareto Felippe
Support type: Scholarships in Brazil - Post-Doctorate