| Full text | |
| Author(s): |
Amaral, Thaeny C.
[1]
;
Miguel, Fabio B.
[2]
;
Couri, Mara R. C.
[2]
;
Corbi, Pedro P.
[3]
;
Carvalho, Marcos A.
[3]
;
Campos, Debora L.
[4]
;
Pavan, Fernando R.
[4]
;
Cuin, Alexandre
[1]
Total Authors: 8
|
| Affiliation: | [1] Univ Fed Juiz de Fora, Dept Quim, Lab Quim BioInorgan, LQBin, Inst Ciencias Exatas, BR-36036330 Juiz de Fora, MG - Brazil
[2] Univ Fed Juiz de Fora, Inst Ciencias Exatas, Dept Quim, BR-36036330 Juiz De Fora, MG - Brazil
[3] Univ Estadual Campinas, UNICAMP, Inst Quim, BR-13083970 Campinas, SP - Brazil
[4] UNESP, Dept Ciencias Biol, Lab Pesquisas TB, Fac Ciencias Farmaceut, BR-14801903 Araraquara, SP - Brazil
Total Affiliations: 4
|
| Document type: | Journal article |
| Source: | Polyhedron; v. 146, p. 166-171, MAY 15 2018. |
| Web of Science Citations: | 2 |
| Abstract | |
Silver(I) and zinc(II) complexes with N,N'-bis(trans-cinnamaldehyde)ethane-1,2-diamine (EnCinn) have been synthesized and characterized by elemental analysis, simultaneous thermogravimetric and differential thermal studies (TG-DTA), infrared (IR), H-1 and C-13 nuclear magnetic resonance (NMR) spectroscopic measurements and electrospray ionization quadrupole time-of-flight mass spectrometry (ESI-QTOF-MS). Crystal and molecular structure descriptions were performed based on powder X-ray diffraction data. The AgEnCinn complex has a polymeric structure where the ligand bridges between two Ag(I) ions, while the ZnEnCinn complex has a monomeric structure with EnCinn acting as chelating ligand. Antimycobacterial assays over Mycobacterium tuberculosis showed the activity of the Ag(I) complex with Minimum Inhibitory Concentration (MIC) value of 22.7 mu mol L-1, while the Zn(II) complex was shown to be inactive over the same experimental conditions. (C) 2018 Elsevier Ltd. All rights reserved. (AU) | |
| FAPESP's process: | 15/25114-4 - Synthesis of New Ag(I), Cu(II), Pd(II) and Pt(II) complexes based on sulfonamides and derivatives: antibacterial activities and application prospects on skin critically colonized wounds. |
| Grantee: | Pedro Paulo Corbi |
| Support Opportunities: | Regular Research Grants |