Carvacrol and linalool co-loaded in beta-cyclodextrin-grafted chitosan nanoparticles as sustainable biopesticide aiming pest control

Author(s):Show less -

Campos, Estefania V. R. ^{[1, 2]} ; Proenca, Patricia L. F. ^[2] ; Oliveira, Jhones L. ^[2] ; Pereira, Anderson E. S. ^[2] ; de Morais Ribeiro, Ligia Nunes ^[1] ; Fernandes, Fabricio O. ^[3] ; Goncalves, Kelly C. ^[3] ; Polanczyk, Ricardo A. ^[3] ; Pasquoto-Stigliani, Tatiane ^[4] ; Lima, Renata ^[4] ; Melville, Cirano C. ^[3] ; Della Vechia, Jaqueline F. ^[3] ; Andrade, Daniel J. ^[3] ; Fraceto, Leonardo F. ^{[1, 2]}

Affiliation

^[1] Univ Estadual Campinas, Dept Biochem & Tissue Biol, Campinas, SP - Brazil

^[2] Sao Paulo State Univ UNESP, Inst Sci & Technol, Sorocaba, SP - Brazil

^[3] Sao Paulo State Univ UNESP, Dept Crop Protect, Coll Agr & Vet Sci, Jaboticabal, SP - Brazil

^[4] Univ Sorocaba, Dept Biotechnol, Sorocaba - Brazil

• Document type: Journal article
• Source: SCIENTIFIC REPORTS; v. 8, MAY 16 2018.
• Web of Science Citations: 13

Abstract

Pesticides are the main tactics for pest control because they reduce the pest population very fast and their efficiency does not depend on abiotic factors. However, the indiscriminate use of these substances can speed up the development of resistant populations and causing environmental contamination. Therefore, alternative methods of pest control are sought, such as the use of botanical compounds. Nanoencapsulation of volatile compounds has been shown to be an important tool that can be used to overcome the lack of stability of these compounds. In this work, we describe the preparation and characterization of chitosan nanoparticles functionalized with beta-cyclodextrin containing carvacrol and linalool. The toxicity and biological activity were evaluated. Decreases of toxicity were observed when the compounds were nanoencapsulated. The nanoparticles presented insecticidal activity against the species Helicoverpa armigera (corn earworm) and Tetranychus urticae (spider mite). In addition, repellent activity and reduction in oviposition were observed for the mites. (AU)

• FAPESP's process: 14/20273-4 - Development of chitosan-²-cyclodextrin nanoparticles for sustained release of carvacrol and linalool aiming agricultural applications
• Grantee: Estefânia Vangelie Ramos Campos
• Support Opportunities: Scholarships in Brazil - Doctorate