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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Action of the Metalloproteinases in Gonadal Remodeling during Sex Reversal in the Sequential Hermaphroditism of the Teleostei Fish Synbranchus marmoratus (Synbranchiformes: Synbranchidae)

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Author(s):
Mazzoni, Talita Sarah [1, 2] ; Lo Nostro, Fabiana Laura [3] ; Antoneli, Fernanda Natalia [4] ; Quagio-Grassiotto, Irani [1, 5]
Total Authors: 4
Affiliation:
[1] State Univ Sao Paulo UNESP, Botucatu Biosci Inst, Dept Morphol, Prof Dr Antonio Celso Wagner Zanin 250, BR-18618689 Botucatu, SP - Brazil
[2] Fed Univ Alfenas UNIFAL, Inst Biomed Sci, Dept Cell & Dev Biol, Gabriel Monteiro da Silva 700, BR-37130001 Alfenas, MG - Brazil
[3] Fac Exact & Nat Sci, Dept Biodivers & Expt Biol, Ciudad Univ, Lab 4 & 78, Piso 4To, Pabellon 2, Buenos Aires, DF - Argentina
[4] Univ Estadual Campinas, Inst Biol, Bertrand Russel S-N, BR-13083865 Campinas, SP - Brazil
[5] Aquaculture Ctr UNESP CAUNESP, Prof Paulo Donato Castellane S-N, BR-14884900 Jaboticabal, SP - Brazil
Total Affiliations: 5
Document type: Journal article
Source: CELLS; v. 7, n. 5 MAY 2018.
Web of Science Citations: 4
Abstract

Teleostei present great plasticity regarding sex change. During sex reversal, the whole gonad including the germinal epithelium undergoes significant changes, remodeling, and neoformation. However, there is no information on the changes that occur within the interstitial compartment. Considering the lack of information, especially on the role played by metalloproteinases (MMPs) in fish gonadal remodeling, the aim of this study was to evaluate the action of MMPs on gonads of sex reversed females of Synbranchus marmoratus, a fresh water protogynic diandric fish. Gonads were processed for light microscopy and blood samples were used for the determination of plasma sex steroid levels. During sex reversal, degeneration of the ovaries occurred and were gradually replaced by the germinal tissue of the male. The action of the MMPs induces significant changes in the interstitial compartment, allowing the reorganization of germinal epithelium. Leydig cells also showed an important role in female to male reversion. The gonadal transition coincides with changes in circulating sex steroid levels throughout sex reversion. The action of the MMPs, in the gonadal remodeling, especially on the basement membrane, is essential for the establishment of a new functional germinal epithelium. (AU)

FAPESP's process: 15/16358-7 - Action of the metalloproteinases (MMPs) and steroid hormones in the gonadal remodeling during the sex inversion in the juvenile and sequential hermaphroditism in Teleostei fish
Grantee:Irani Quagio Grassiotto
Support type: Regular Research Grants
FAPESP's process: 14/00868-3 - Action of the metalloproteinases (MMPs) in the gonadal remodeling during the sex inversion in the juvenile and sequential hermaphroditism in Teleostei fish
Grantee:Talita Sarah Mazzoni
Support type: Scholarships in Brazil - Post-Doctorate