| Full text | |
| Author(s): |
Angelica Miki Stein
[1]
;
Thays Martins Vital Silva
;
Flávia Gomes de Melo Coelho
;
Franciel José Arantes
[4]
;
José Luiz Riani Costa
[5]
;
Elizabeth Teodoro
[6]
;
Ruth Ferreira Santos-Galduróz
[7]
Total Authors: 7
|
| Affiliation: | [1] Universidade Estadual Paulista. Physical Activity and Aging Lab. Institute of Biosciences - Brasil
[4] Universidade Estadual Paulista. Physical Activity and Aging Lab. Institute of Biosciences - Brasil
[5] Universidade Estadual Paulista. Physical Activity and Aging Lab. Institute of Biosciences - Brasil
[6] University Federal of ABC. Center of Mathematics, Computing and Cognition - Brasil
[7] University Federal of ABC. Center of Mathematics, Computing and Cognition - Brasil
Total Affiliations: 7
|
| Document type: | Journal article |
| Source: | Dement. Neuropsychol.; v. 12, n. 2, p. 114-122, 2018-06-00. |
| Abstract | |
ABSTRACT One of hypothetical mechanisms related to cognition is exercise-induced IGF-1. Objective: The aim of this study was to analyze the effects of exercise on IGF-1 levels and cognition in the elderly. Methods: The article searches were conducted on Pubmed, Web of Science, PsycINFO and Scielo databases and reviewed according to PRISMA guidelines. The inclusion criteria were: [1] original articles published up to 2017; [2] samples including elderly; [3] protocols including physical exercise; [4] longitudinal studies having exercise as main outcome; [5] assessment of IGF-1; [6] cognition assessment. Results: Seven studies were included in this review. Three of the studies showed an exercise-induced increase in IGF-1; three found stable IGF-1 levels and one found a reduction in IGF-1; with and without improvement in cognition. Conclusion: Disparities in the type of physical exercise, protocols and samples under different conditions hinder the establishment of a consensus on IGF-1, cognition and physical exercise. (AU) | |
| FAPESP's process: | 13/19729-0 - Effect of aerobic training in levels of insulin-like growth factor-1 and cognitive functions in Alzheimer's Disease |
| Grantee: | Angelica Miki Stein |
| Support Opportunities: | Scholarships in Brazil - Doctorate (Direct) |