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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The epidemiology of personality disorders in the Sao Paulo Megacity general population

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Author(s):
Santana, Geilson Lima [1] ; Coelho, Bruno Mendonca [1] ; Wang, Yuan-Pang [1] ; Porto Chiavegatto Filho, Alexandre Dias [2] ; Viana, Maria Carmen [3] ; Andrade, Laura Helena [1]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Med Sch, Sect Psychiat Epidemiol, Inst & Dept Psychiat LIM 23, Sao Paulo, SP - Brazil
[2] Univ Sao Paulo, Sch Publ Hlth, Dept Epidemiol, Sao Paulo, SP - Brazil
[3] Univ Fed Espirito Santo, Dept Social Med, Vitoria, ES - Brazil
Total Affiliations: 3
Document type: Journal article
Source: PLoS One; v. 13, n. 4 APR 24 2018.
Web of Science Citations: 1
Abstract

Introduction Most studies on the epidemiology of personality disorders (PDs) have been conducted in high-income countries and may not represent what happens in most part of the world. In the last decades, population growth has been concentrated in low-and middle-income countries, with rapid urbanization, increasing inequalities and escalation of violence. Our aim is to estimate the prevalence of PDs in the Sao Paulo Metropolitan Area, one of the largest megacities of the world. We examined sociodemographic correlates, the influence of urban stressors, the comorbidity with other mental disorders, functional impairment and treatment. Methods A representative household sample of 2,942 adults was interviewed using the WHO-Composite International Diagnostic Interview and the International Personality Disorder Examination-Screening Questionnaire. Diagnoses were multiply imputed, and analyses used multivariable regression. Results and discussion Prevalence estimates were 4.3% (Cluster A), 2.7% (Cluster B), 4.6% (Cluster C) and 6.8% (any PD). Cumulative exposure to violence was associated with all PDs except Cluster A, although urbanicity, migration and neighborhood social deprivation were not significant predictors. Comorbidity was the rule, and all clusters were associated with other mental disorders. Lack of treatment is a reality in Greater Sao Paulo, and this is especially true for PDs. With the exception of Cluster C, non-comorbid PDs remained largely untreated in spite of functional impairment independent of other mental disorders. Conclusion Personality disorders are prevalent, clinically significant and undertreated, and public health strategies must address the unmet needs of these subjects. Our results may reflect what happens in other developing world megacities, and future studies are expected in other low- and middle-income countries. (AU)

FAPESP's process: 03/00204-3 - Epidemiological study of psychiatric disorders in the São Paulo Metropolitan Region: prevalence, risk factors, and social and economical burden
Grantee:Laura Helena Silveira Guerra de Andrade
Support Opportunities: Research Projects - Thematic Grants