Chemical and biological studies of symbiotic bacteria isolated from Atta sexdens r...
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Pyrazines from bacteria and ants: convergent chemistry within an ecological niche
Full text
| |
| Author(s): |
Silva-Junior, Eduardo A.
[1]
;
Ruzzini, Antonio C.
[2, 3]
;
Paludo, Camila R.
[1]
;
Nascimento, Fabio S.
[4]
;
Currie, Cameron R.
[5]
;
Clardy, Jon
[2]
;
Pupo, Monica T.
[1]
Total Authors: 7
|
| Affiliation: | [1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, BR-14040903 Ribeirao Preto, SP - Brazil
[2] Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 - USA
[3] Univ Saskatchewan, Dept Vet Microbiol, Saskatoon, SK S7N 5B4 - Canada
[4] Univ Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Dept Biol, BR-14040901 Ribeirao Preto, SP - Brazil
[5] Univ Wisconsin, Dept Bacteriol, Madison, WI 53706 - USA
Total Affiliations: 5
|
| Document type: | Journal article |
| Source: | SCIENTIFIC REPORTS; v. 8, FEB 7 2018. |
| Web of Science Citations: | 7 |
| Abstract | |
Ants use pheromones to coordinate their communal activity. Volatile pyrazines, for instance, mediate food resource gathering and alarm behaviors in different ant species. Here we report that leaf-cutter ant-associated bacteria produce a family of pyrazines that includes members previously identified as ant trail and alarm pheromones. We found that L-threonine induces the bacterial production of the trail pheromone pyrazines, which are common for the host leaf-cutter ants. Isotope feeding experiments revealed that L-threonine along with sodium acetate were the biosynthetic precursors of these natural products and a biosynthetic pathway was proposed. (AU) | |
| FAPESP's process: | 13/50954-0 - Novel therapeutic agents from the bacterial symbionts of Brazilian invertebrates |
| Grantee: | Mônica Tallarico Pupo |
| Support type: | BIOTA-FAPESP Program - Thematic Grants |
| FAPESP's process: | 12/24204-1 - Natural products involved in chemical and biological interactions of microorganisms associated to nests of the leaf-cutting ants Atta Sexdens rubropilosa |
| Grantee: | Eduardo Afonso da Silva Junior |
| Support type: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 14/24330-2 - Chemical and biological studies of symbiotic bacteria isolated from Atta sexdens rubropilosa |
| Grantee: | Eduardo Afonso da Silva Junior |
| Support type: | Scholarships abroad - Research Internship - Doctorate |
| FAPESP's process: | 15/25301-9 - Evaluating the exogenous and endogenous mechanisms influencing variability of cuticular hydrocarbons in neotropical social insects |
| Grantee: | Fábio Santos do Nascimento |
| Support type: | Regular Research Grants |
| FAPESP's process: | 12/22487-6 - Chemical and biological study of natural products of microorganisms associated with stingless bee species Scaptotrigona depilis |
| Grantee: | Camila Raquel Paludo |
| Support type: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 13/04092-7 - Natural products from microorganisms associated with the social insects Scaptotrigona depilis and Atta sexdens rubropilosa: chemical characterization, biological and ecological functions |
| Grantee: | Mônica Tallarico Pupo |
| Support type: | Regular Research Grants |