Advanced search
Start date
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Pyrazines from bacteria and ants: convergent chemistry within an ecological niche

Full text
Silva-Junior, Eduardo A. [1] ; Ruzzini, Antonio C. [2, 3] ; Paludo, Camila R. [1] ; Nascimento, Fabio S. [4] ; Currie, Cameron R. [5] ; Clardy, Jon [2] ; Pupo, Monica T. [1]
Total Authors: 7
[1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, BR-14040903 Ribeirao Preto, SP - Brazil
[2] Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 - USA
[3] Univ Saskatchewan, Dept Vet Microbiol, Saskatoon, SK S7N 5B4 - Canada
[4] Univ Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Dept Biol, BR-14040901 Ribeirao Preto, SP - Brazil
[5] Univ Wisconsin, Dept Bacteriol, Madison, WI 53706 - USA
Total Affiliations: 5
Document type: Journal article
Source: SCIENTIFIC REPORTS; v. 8, FEB 7 2018.
Web of Science Citations: 11

Ants use pheromones to coordinate their communal activity. Volatile pyrazines, for instance, mediate food resource gathering and alarm behaviors in different ant species. Here we report that leaf-cutter ant-associated bacteria produce a family of pyrazines that includes members previously identified as ant trail and alarm pheromones. We found that L-threonine induces the bacterial production of the trail pheromone pyrazines, which are common for the host leaf-cutter ants. Isotope feeding experiments revealed that L-threonine along with sodium acetate were the biosynthetic precursors of these natural products and a biosynthetic pathway was proposed. (AU)

FAPESP's process: 13/50954-0 - Novel therapeutic agents from the bacterial symbionts of Brazilian invertebrates
Grantee:Mônica Tallarico Pupo
Support type: BIOTA-FAPESP Program - Thematic Grants
FAPESP's process: 12/24204-1 - Natural products involved in chemical and biological interactions of microorganisms associated to nests of the leaf-cutting ants Atta Sexdens rubropilosa
Grantee:Eduardo Afonso da Silva Junior
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 14/24330-2 - Chemical and biological studies of symbiotic bacteria isolated from Atta sexdens rubropilosa
Grantee:Eduardo Afonso da Silva Junior
Support type: Scholarships abroad - Research Internship - Doctorate
FAPESP's process: 15/25301-9 - Evaluating the exogenous and endogenous mechanisms influencing variability of cuticular hydrocarbons in Neotropical social insects
Grantee:Fábio Santos do Nascimento
Support type: Regular Research Grants
FAPESP's process: 12/22487-6 - Chemical and biological study of natural products of microorganisms associated with stingless bee species Scaptotrigona depilis
Grantee:Camila Raquel Paludo
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 13/04092-7 - Natural products from microorganisms associated with the social insects Scaptotrigona depilis and Atta sexdens rubropilosa: chemical characterization, biological and ecological functions
Grantee:Mônica Tallarico Pupo
Support type: Regular Research Grants