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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Pyrazines from bacteria and ants: convergent chemistry within an ecological niche

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Author(s):
Silva-Junior, Eduardo A. [1] ; Ruzzini, Antonio C. [2, 3] ; Paludo, Camila R. [1] ; Nascimento, Fabio S. [4] ; Currie, Cameron R. [5] ; Clardy, Jon [2] ; Pupo, Monica T. [1]
Total Authors: 7
Affiliation:
[1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, BR-14040903 Ribeirao Preto, SP - Brazil
[2] Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 - USA
[3] Univ Saskatchewan, Dept Vet Microbiol, Saskatoon, SK S7N 5B4 - Canada
[4] Univ Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Dept Biol, BR-14040901 Ribeirao Preto, SP - Brazil
[5] Univ Wisconsin, Dept Bacteriol, Madison, WI 53706 - USA
Total Affiliations: 5
Document type: Journal article
Source: SCIENTIFIC REPORTS; v. 8, FEB 7 2018.
Web of Science Citations: 7
Abstract

Ants use pheromones to coordinate their communal activity. Volatile pyrazines, for instance, mediate food resource gathering and alarm behaviors in different ant species. Here we report that leaf-cutter ant-associated bacteria produce a family of pyrazines that includes members previously identified as ant trail and alarm pheromones. We found that L-threonine induces the bacterial production of the trail pheromone pyrazines, which are common for the host leaf-cutter ants. Isotope feeding experiments revealed that L-threonine along with sodium acetate were the biosynthetic precursors of these natural products and a biosynthetic pathway was proposed. (AU)

FAPESP's process: 13/50954-0 - Novel therapeutic agents from the bacterial symbionts of Brazilian invertebrates
Grantee:Mônica Tallarico Pupo
Support type: BIOTA-FAPESP Program - Thematic Grants
FAPESP's process: 12/24204-1 - Natural products involved in chemical and biological interactions of microorganisms associated to nests of the leaf-cutting ants Atta Sexdens rubropilosa
Grantee:Eduardo Afonso da Silva Junior
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 14/24330-2 - Chemical and biological studies of symbiotic bacteria isolated from Atta sexdens rubropilosa
Grantee:Eduardo Afonso da Silva Junior
Support type: Scholarships abroad - Research Internship - Doctorate
FAPESP's process: 15/25301-9 - Evaluating the exogenous and endogenous mechanisms influencing variability of cuticular hydrocarbons in neotropical social insects
Grantee:Fábio Santos do Nascimento
Support type: Regular Research Grants
FAPESP's process: 12/22487-6 - Chemical and biological study of natural products of microorganisms associated with stingless bee species Scaptotrigona depilis
Grantee:Camila Raquel Paludo
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 13/04092-7 - Natural products from microorganisms associated with the social insects Scaptotrigona depilis and Atta sexdens rubropilosa: chemical characterization, biological and ecological functions
Grantee:Mônica Tallarico Pupo
Support type: Regular Research Grants