Advanced search
Start date
Betweenand
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Development of Ti-15Zr-Mo alloys for applying as implantable biomedical devices

Full text
Author(s):
Correa, D. R. N. [1, 2] ; Kuroda, P. A. B. [3, 1] ; Lourenco, M. L. [3, 1] ; Fernandes, C. J. C. [4] ; Buzalaf, M. A. R. [5] ; Zambuzzi, W. F. [1, 4] ; Grandini, C. R. [3, 1]
Total Authors: 7
Affiliation:
[1] IBTN Br Inst Biomat Tribocorros & Nanomed, Brazilian Branch, BR-17033360 Bauru, SP - Brazil
[2] IFSP Fed Inst Educ Sci & Technol, BR-18095410 Sorocaba, SP - Brazil
[3] UNESP Univ Estadual Paulista, Lab Anelasticidade & Biomat, BR-17033360 Bauru, SP - Brazil
[4] UNESP Univ Estadual Paulista, Dept Quim & Bioquim, BR-18618970 Botucatu, SP - Brazil
[5] Univ Sao Paulo, Fac Odontol, Dept Ciencias Biol, BR-17012901 Bauru, SP - Brazil
Total Affiliations: 5
Document type: Journal article
Source: Journal of Alloys and Compounds; v. 749, p. 163-171, JUN 15 2018.
Web of Science Citations: 13
Abstract

In this study, the effect of molybdenum content in Ti-15Zr-based alloys (wt%) was analyzed in terms of crystalline structure, microstructure, selected mechanical properties, and cytotoxicity. The samples were produced by argon arc-melting followed by hot rolling and heat treatment processes. The crystalline structure and microstructure were dependent of both alloying elements (zirconium and molybdenum). Ti-15Zr alloy displayed only laths of alpha ` phase, while the alloys up to Ti-15Zr-10Mo exhibited different proportions of alpha `, alpha `', and beta phases. Molybdenum content higher than 12.5 wt% fully stabilized the beta phase. Vickers microhardness values of Ti-15Zr-Mo alloys were higher than those of CP-Ti due to solid solution and phase precipitation strengthening. Young's modulus values of Ti-15Zr-Mo alloys were lower than those of CP-Ti due to b phase stabilization. Cytotoxicity levels of Ti-15Zr-Mo alloys were within a tolerable range for biomedical purposes. In addition, we observed molybdenum content in Ti-15Zr-based alloys promoted an increase on pre-osteoblast adhesion up to 3 h of adhesion's time. Thus, Ti-15Zr-15Mo alloy presented better combination of properties than some traditional metallic biomaterials. (C) 2018 Elsevier B. V. All rights reserved. (AU)

FAPESP's process: 12/22742-6 - Preparation a characterization of a titanium alloy containing zirconium and molybdenum for biomedical applications
Grantee:Pedro Akira Bazaglia Kuroda
Support Opportunities: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 14/22689-3 - Microvesicle/proteins-mediated paracrine signaling among bone and endothelial cells during bone development and regeneration
Grantee:Willian Fernando Zambuzzi
Support Opportunities: Research Grants - Young Investigators Grants
FAPESP's process: 10/20440-7 - Effect of substitutional and interstitial elements in the mechanical properties and biocompatibility of Ti-15Zr-xMo alloys
Grantee:Diego Rafael Nespeque Correa
Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
FAPESP's process: 15/00851-6 - Biofunctionalization of Ti-15Zr-BASED alloys with molybdenum addition and some surface modifications
Grantee:Diego Rafael Nespeque Correa
Support Opportunities: Scholarships in Brazil - Post-Doctoral