Synthesis and characterization of magnetic-molecularly imprinted polymers for the HPLC-UV analysis of ametryn

Author(s)

Khan, Sabir ^{[1, 2]} ; Hussain, Sajjad ^[3] ; Wong, Ademar ^{[1, 2]} ; Foguel, Marcos Vinicius ^{[1, 2]} ; Goncalves, Luis Moreira ^[4] ; Pividori Gurgo, Maria Isabel ^[5] ; Taboada Sotomayor, Maria del Pilar ^{[1, 2]}

Affiliation

^[1] Univ Estadual Paulista, UNESP, Inst Quim, Dept Quim Analit, Araraquara, SP - Brazil

^[2] Natl Inst Alternat Technol Detect Toxicol Evaluat, Araraquara, SP - Brazil

^[3] GIK Inst Engn Sci & Technol, Fac Mat & Chem Engn, Topi - Pakistan

^[4] Univ Porto, Fac Ciencias, Dept Quim & Bioquim, REQUIMTE LAQV, Oporto - Portugal

^[5] Univ Autonoma Barcelona, Dept Analyt Chem, Barcelona - Spain

• Document type: Journal article
• Source: REACTIVE & FUNCTIONAL POLYMERS; v. 122, p. 175-182, JAN 2018.
• Web of Science Citations: 11

Abstract

Magnetic molecularly imprinted polymer (mag-MIP) were developed for the analysis of ametryn (4-Nethyl-6-methylsulfanyl-2-N-propan-2-yl-1,3,5-triazine-2,4-diamine), a popular triazine herbicide. Iron oxide (Fe3O4) nanoparticles were synthetized, and then modified with tetraethoxysilane (TEOS) and 3-mercaptopropyl-trimethoxysilane (MPS). Then MIPs' polymerimerization occurred in the nanoparticles' surface, using ethylene-glycol-dimethacrylate (EGDMA) as the building monomer, 2,2'-azobis(2-methylpropionitrile) (AIBN) as the radical initiator, and 2-vinylpyridine as the functional monomer. The functional monomer was previously chosen by computational simulation. The mag-MIPs' adsorption behavior well-fitted a Langmuir model (q(m)of 8.6 mg g(-1),K-L of 5.2 L mg(-1)) and pseudo first order kinetics (k(1) of 2.5 x 10(-4) s(-1)). The developed analytical methodology, using high-performance liquid chromatography with UV detection (HPLC-UV), showed suitable selectivity and had a limit of detection (LOD) and quantification (LOQ) of 25 and 82 nmol L-1, respectively. (AU)

• FAPESP's process: 16/06926-0 - Development and application of new nanostructured chemical sensors and applications of new nanostructured chemical sensors based on biomimetic polymers
• Grantee: Maria Del Pilar Taboada Sotomayor
• Support Opportunities: Research Grants - Visiting Researcher Grant - International
• FAPESP's process: 14/25264-3 - Development and application of new nanoestructurated chemical sensors based on biomimetic polymers
• Grantee: Maria Del Pilar Taboada Sotomayor
• Support Opportunities: Regular Research Grants