| Full text | |
| Author(s): |
Ortega, Humberto E.
[1]
;
Batista, Jr., Joao M.
[2]
;
Melo, Weilan G. P.
[1]
;
Clardy, Jon
[3]
;
Pupo, Monica T.
[1]
Total Authors: 5
|
| Affiliation: | [1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, BR-14040903 Ribeirao Preto, SP - Brazil
[2] Fed Univ Sao Carlos UFSCar, Dept Chem, Rod Washington Luis Km 235, BR-13565905 Sao Carlos, SP - Brazil
[3] Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 - USA
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | Tetrahedron Letters; v. 58, n. 50, p. 4721-4723, DEC 13 2017. |
| Web of Science Citations: | 4 |
| Abstract | |
The known antibiotic and cytotoxic compounds griseorhodin A (1) and griseorhodin C (2) were produced in solid culture by Streptomyces puniceus AB10, which was isolated from the leaf-cutter ant Acromyrmex rugosus rugosus. Their absolute configurations were unambiguously established as 6S,6aR,7S,8S and 6R,6aR,7S,8R, respectively, using vibrational circular dichroism (VCD) and density functional theory (DFT) calculations. (C) 2017 Elsevier Ltd. All rights reserved. (AU) | |
| FAPESP's process: | 15/07089-2 - Vibrational chiroptical spectroscopy for stereochemical characterization of small molecules and macromolecules |
| Grantee: | João Marcos Batista Junior |
| Support Opportunities: | Scholarships in Brazil - Young Researchers |
| FAPESP's process: | 14/25222-9 - Vibrational chiroptical spectroscopy for stereochemical characterization of small molecules and macromolecules |
| Grantee: | João Marcos Batista Junior |
| Support Opportunities: | Research Grants - Young Investigators Grants |
| FAPESP's process: | 15/01001-6 - Discovering bacterial symbionts diversity associated with ants in different Brazilian biomes |
| Grantee: | Weilan Gomes da Paixão Melo |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 13/50954-0 - Novel therapeutic agents from the bacterial symbionts of Brazilian invertebrates |
| Grantee: | Mônica Tallarico Pupo |
| Support Opportunities: | BIOTA-FAPESP Program - Thematic Grants |