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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Light-emitting diode therapy (photobiomodulation) effects on oxygen uptake and cardiac output dynamics during moderate exercise transitions: a randomized, crossover, double-blind, and placebo-controlled study

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Author(s):
Beltrame, Thomas [1, 2] ; Ferraresi, Cleber [3, 4, 5, 6, 7] ; Parizotto, Nivaldo Antonio [4, 5, 7] ; Bagnato, Vanderlei Salvador [3] ; Hughson, Richard L. [2, 8]
Total Authors: 5
Affiliation:
[1] Conselho Nacl Desenvolvimento Cient & Tecnol CNPq, Brasilia, DF - Brazil
[2] Univ Waterloo, Fac Appl Hlth Sci, Waterloo, ON - Canada
[3] Univ Sao Paulo, Phys Inst Sao Carlos, Opt Grp, Sao Carlos, SP - Brazil
[4] Univ Fed Sao Carlos, Postgrad Program Biotechnol, Sao Paulo - Brazil
[5] Univ Fed Sao Carlos, Dept Phys Therapy, Lab Electrothermophotherapy, Sao Paulo - Brazil
[6] Univ Sagrado Coracao, Phys Therapy Dept, Postgrad Program Phys Therapy Funct Hlth, Sao Paulo - Brazil
[7] Univ Brasil, Postgrad Program Biomed Engn, Sao Paulo - Brazil
[8] Schlegel Univ Waterloo, Res Inst Aging, 250 Laurelwood Dr, Waterloo, ON N2J 0E2 - Canada
Total Affiliations: 8
Document type: Journal article
Source: Lasers in Medical Science; v. 33, n. 5, p. 1065-1071, JUL 2018.
Web of Science Citations: 1
Abstract

Light-emitting diodes (LEDs) might have a beneficial impact on cytochrome-c oxidase enzyme activity. Thus, it was hypothesized that photobiomodulation by light-emitting diode therapy (LEDT) could influence aerobic metabolism dynamics. Possible LEDT-mediated aerobic improvements were investigated mainly by a precise characterization of the pulmonary O (2) uptake dynamics during moderate exercise transitions. Eight healthy young adults were enrolled in this randomized, double-blind, placebo-controlled, crossover study. A multi-diode array of LEDs was used for muscular pre-conditioning 30 min and 6 h before exercise testing. Pulmonary O (2) uptake, carbon dioxide output, cardiac output, heart rate, stroke volume, and total arteriovenous oxygen difference dynamics were evaluated by frequency domain analysis. Comparisons revealed no statistical (p > 0.05) differences between LEDT and placebo, suggesting no significant changes in aerobic system dynamics. These results challenge earlier publications that reported changes in pulmonary O (2) uptake during incremental exercise until exhaustion after LEDT. Perhaps, increments in peak pulmonary O (2) uptake after LEDT may be a consequence of higher exercise tolerance caused by non-aerobic-related factors as opposed to an improved aerobic response. (AU)

FAPESP's process: 10/07194-7 - Use of low-level laser and light-emitting diode therapy to increase muscle performance: from in vitro and experimental studies to clinical applications
Grantee:Cleber Ferraresi
Support type: Scholarships in Brazil - Doctorate