Evaluation of acute effect of phototherapy with Light Emitting Diode (led) on muscle and pulmonary oxygen consumption in patients with diabetes mellitus

• Grant number: 13/07953-3
• Support Opportunities: Regular Research Grants
• Start date: May 01, 2014
• End date: April 30, 2016
• Field of knowledge: Health Sciences - Physiotherapy and Occupational Therapy
• Principal Investigator: Aparecida Maria Catai
• Grantee: Aparecida Maria Catai
• Host Institution: Centro de Ciências Biológicas e da Saúde (CCBS). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil
• Associated researchers: Alberto Porta ; Audrey Borghi Silva ; Nivaldo Antonio Parizotto ; Richard L. Hughson ; Vanderlei Salvador Bagnato

Abstract

Type 2 diabetes mellitus (DM2) is responsible to significant reduction in life quality due it negative impact in physical exercise capacity. Impairment in cardiopulmonary fitness and low oxygen uptake peak values (VO2peak) in exercise tests has been associated with many factors involved in diabetes complications. Phototherapy is a resource largely utilized due it action in biological systems and it may be adjuvant to exercise to improve muscular efficiency and increase aerobic capacity. Therefore, we hypothesized that this resource adjuvant with physical exercise may be benefit to populations with DM. Thus, the objective of this study will be evaluate the acute effect of phototherapy through light emitting diode (LED) on muscle and pulmonary oxygen uptake kinetics, even as, heart rate and arterial pressure kinetics in subjects with DM2, during dynamic physical exercise of constant workload and moderate intensity, to evaluate the systemic cardiovascular adjustments involving photo-stimulation application. Also, to verify the therapeutic potential of phototherapy in improve physical exercise tolerance and compare the results between DM2 and health individuals to see if the phototherapy effects are different between groups. (AU)

Scientific publications

(9)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MILAN-MATTOS, JULIANA CRISTINA; FRANCISCO, CRISTINA DE OLIVEIRA; FERROLI-FABRICIO, AMANDA MAGDALENA; MINATEL, VINICIUS; APARECIDA MARCONDES, ANA CAROLINA; PORTA, ALBERTO; BELTRAME, THOMAS; PARIZOTTO, NIVALDO ANTONIO; FERRARESI, CLEBER; BAGNATO, VANDERLEI SALVADOR; et al. Acute effect of photobiomodulation using light-emitting diodes (LEDs) on baroreflex sensitivity during and after constant loading exercise in patients with type 2 diabetes mellitus. Lasers in Medical Science, v. 35, n. 2, p. 329-336, MAR 2020. (13/07953-3)

GALDINO, GABRIELA AGUIAR MESQUITA; SILVA, LUIZ EDUARDO VIRGILIO; MOURA-TONELLO, SILVIA CRISTINA GARCIA; MILAN-MATTOS, JULIANA CRISTINA; LINARES, STEPHANIE NOGUEIRA; PORTA, ALBERTO; DA SILVA, THAIS MARQUES; FAZAN JR, RUBENS; BELTRAME, THOMAS; CATAI, APARECIDA MARIA. Heart rate fragmentation is impaired in type 2 diabetes mellitus patients. Diabetes Research and Clinical Practice, v. 196, p. 8-pg., 2022-12-21. (16/22215-7, 10/52070-4, 13/07953-3)

FRANCISCO, CRISTINA DE OLIVEIRA; BELTRAME, THOMAS; HUGHSON, RICHARD L.; MILAN-MATTOS, JULIANA CRISTINA; FERROLI-FABRICIO, AMANDA MAGDALENA; BENZE, BENEDITO GALVAO; FERRARESI, CLEBER; PARIZOTTO, NIVALDO ANTONIO; BAGNATO, VANDERLEI SALVADOR; BORGHI-SILVA, AUDREY; et al. Effects of light-emitting diode therapy (LEDT) on cardiopulmonary and hemodynamic adjustments during aerobic exercise and glucose levels in patients with diabetes mellitus: A randomized, crossover, double-blind and placebo-controlled clinical trial. COMPLEMENTARY THERAPIES IN MEDICINE, v. 42, p. 178-183, FEB 2019. (15/20512-1, 13/07953-3, 13/08183-7)

GARCIA DE MOURA-TONELLO, SILVIA CRISTINA; PORTA, ALBERTO; MARCHI, ANDREA; FAGUNDES, ALESSANDRA DE ALMEIDA; FRANCISCO, CRISTINA DE OLIVEIRA; REHDER-SANTOS, PATRICIA; MILAN-MATTOS, JULIANA CRISTINA; SIMOES, RODRIGO POLAQUINI; GOIS, MARIANA DE OLIVEIRA; CATAI, APARECIDA MARIA. Cardiovascular Variability Analysis and Baroreflex Estimation in Patients with Type 2 Diabetes in Absence of Any Manifest Neuropathy. PLoS One, v. 11, n. 3, MAR 17 2016. (13/07953-3, 10/52070-4)

DE MARIA, BEATRICE; VECCHIA, LAURA ADELAIDE DALLA; BARI, VLASTA; CAIRO, BEATRICE; GELPI, FRANCESCA; PEREGO, FRANCESCA; TAKAHASHI, ANIELLE CHRISTINE MEDEIROS; MILAN-MATTOS, JULIANA CRISTINA; MINATEL, VINICIUS; REHDER-SANTOS, PATRICIA; et al. The percentage of cardiac baroreflex sequences is independent from the sign of arterial pressure variations in healthy subjects. 2022 12TH CONFERENCE OF THE EUROPEAN STUDY GROUP ON CARDIOVASCULAR OSCILLATIONS (ESGCO), v. N/A, p. 2-pg., 2022-01-01. (13/07953-3)

LINARES, STEPHANIE NOGUEIRA; BELTRAME, THOMAS; FERRARESI, CLEBER; GALDINO, GABRIELA AGUIAR MESQUITA; CATAI, APARECIDA MARIA. Photobiomodulation effect on local hemoglobin concentration assessed by near-infrared spectroscopy in humans. Lasers in Medical Science, v. 35, n. 3, p. 641-649, APR 2020. (18/19016-8, 13/07953-3, 17/09639-5)

FRANCISCO, CRISTINA DE OLIVEIRA; BELTRAME, THOMAS; FERRARESI, CLEBER; PARIZOTTO, NIVALDO ANTONIO; BAGNATO, VANDERLEI SALVADOR; SILVA, AUDREY BORGHI; BENZE, BENEDITO GALVAO; PORTA, ALBERTO; CATAI, APARECIDA MARIA. Evaluation of acute effect of light-emitting diode (LED) phototherapy on muscle deoxygenation and pulmonary oxygen uptake kinetics in patients with diabetes mellitus: study protocol for a randomized controlled trial. Trials, v. 16, DEC 15 2015. (13/07953-3, 13/08183-7)

LINARES, STEPHANIE N.; BELTRAME, THOMAS; GALDINO, GABRIELA A. M.; FRADE, MARIA CECILIA M.; MILAN-MATTOS, JULIANA C.; GOIS, MARIANA O.; BORGHI-SILVA, AUDREY; DE BIASE, PRISCILA F.; MANCHADO-GOBATTO, FULVIA B.; BAGNATO, VANDERLEI S.; et al. Dose Response Effect of Photobiomodulation on Hemodynamic Responses and Glucose Levels in Men with Type 2 Diabetes: A Randomized, Crossover, Double-Blind, Sham-Controlled Trial. PHOTONICS, v. 9, n. 7, p. 15-pg., 2022-07-01. (17/09639-5, 13/07953-3)

CORREA, MIKAELA DA SILVA; CATAI, APARECIDA M.; MILAN-MATTOS, JULIANA C.; PORTA, ALBERTO; DRIUSSO, PATRICIA. Is pelvic floor muscle training able to alter the response of cardiovascular autonomic modulation and provide a possible cardiovascular benefit to pregnant women?. NEUROUROLOGY AND URODYNAMICS, v. 39, n. 8, AUG 2020. (11/20046-0, 13/07953-3)