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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Catalytic Enantioselective Allylations of Acetylenic Aldehydes via 2-Propanol-Mediated Reductive Coupling

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Brito, Gilmar A. [1, 2] ; Della-Felice, Franco [1, 2] ; Luo, Guoshun [2] ; Burns, Alexander S. [3] ; Pilli, Ronaldo A. [1] ; Rychnovsky, Scott D. [3] ; Krische, Michael J. [2]
Total Authors: 7
[1] Univ Campinas UNICAMP, Inst Chem, POB 6154, BR-13083970 Campinas, SP - Brazil
[2] Univ Texas Austin, Dept Chem, Austin, TX 78712 - USA
[3] Univ Calif Irvine, Dept Chem, Nat Sci 2 1102, Irvine, CA 92697 - USA
Total Affiliations: 3
Document type: Journal article
Source: ORGANIC LETTERS; v. 20, n. 13, p. 4144-4147, JUL 6 2018.
Web of Science Citations: 4

Cyclometalated pi-allyliridium C,O-benzoates modified by (S)-SEGPHOS or (S)-Cl,OMe-BIPHEP catalyze enantioselective 2-propanol-mediated reductive couplings of diverse nonmetallic allyl pronucleophiles with the acetylenic aldehyde TIPSC CCHO. Absolute stereochemistries of the resulting secondary homoallylic-propargylic alcohols were assigned using Rychnovsky's competing enantioselective conversion method. (AU)

FAPESP's process: 17/18487-4 - Synthesis and structural validation of phosdiecin A
Grantee:Franco Della Felice
Support type: Scholarships abroad - Research Internship - Doctorate (Direct)
FAPESP's process: 17/00734-5 - Catalytic synthesis of Type II polyketides via Hydrogen-Mediated C-C bond formation
Grantee:Gilmar Araujo Brito Junior
Support type: Scholarships abroad - Research Internship - Post-doctor