Advanced search
Start date
Betweenand
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Synthesis and 3D Interconnected Nanostructured h-BN-Based Biocomposites by Low-Temperature Plasma Sintering: Bone Regeneration Applications

Full text
Author(s):
Show less -
Gautam, Chandkiram [1, 2] ; Chakravarty, Dibyendu [3, 4] ; Gautam, Amarendra [1] ; Tiwary, Chandra Sekhar [2, 4] ; Woellner, Cristiano Francisco [2, 5] ; Mishra, Vijay Kumar [6] ; Ahmad, Naseer [6] ; Ozden, Sehmus [2] ; Jose, Sujin [7] ; Biradar, Santoshkumar [2] ; Vajtai, Robert [2] ; Trivedi, Ritu [6] ; Galvao, Douglas S. [5] ; Ajayan, Pulickel M. [2]
Total Authors: 14
Affiliation:
[1] Univ Lucknow, Dept Phys, Lucknow 226007, Uttar Pradesh - India
[2] Rice Univ, Dept Mat Sci & Nano Engn, Houston, TX 77005 - USA
[3] Int Adv Res Ctr Powder Met & New Mat ARCI, Hyderabad 500005, Telangana - India
[4] Indian Inst Technol, Dept Mat Sci & Engn, Gandhinagar, Gujarat - India
[5] Univ Estadual Campinas, UNICAMP, Appl Phys Dept, BR-13083859 Campinas, SP - Brazil
[6] CSIR Cent Drug Res Inst, Endocrinol Div, Lucknow 226031, Uttar Pradesh - India
[7] Madurai Kamaraj Univ, Sch Phys, Madurai 625021, Tamil Nadu - India
Total Affiliations: 7
Document type: Journal article
Source: ACS OMEGA; v. 3, n. 6, p. 6013-6021, JUN 2018.
Web of Science Citations: 5
Abstract

Recent advances and demands in biomedical applications drive a large amount of research to synthesize easily scalable low-density, high-strength, and wear-resistant biomaterials. The chemical inertness with low density combined with high strength makes h-BN one of the promising materials for such application. In this work, three-dimensional hexagonal boron nitride (h-BN) interconnected with boron trioxide (B2O3) was prepared by easily scalable and energy efficient spark plasma sintering (SPS) process. The composite structure shows significant densification (1.6-1.9 g/cm(3)) and high surface area (0.97-14.5 m(2)/g) at an extremely low SPS temperature of 250 degrees C. A high compressive strength of 291 MPa with a reasonably good wear resistance was obtained for the composite structure. The formation of strong covalent bonds between h-BN and B2O3 was formulated and established by molecular dynamics simulation. The composite showed significant effect on cell viability/proliferation. It shows a high mineralized nodule formation over the control, which suggests its use as a possible osteogenic agent in bone formation. (AU)

FAPESP's process: 16/12340-9 - Structural and mechanical properties of carbon-based foams
Grantee:Cristiano Francisco Woellner
Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
FAPESP's process: 13/08293-7 - CCES - Center for Computational Engineering and Sciences
Grantee:Munir Salomao Skaf
Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC