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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Synthesis and 3D Interconnected Nanostructured h-BN-Based Biocomposites by Low-Temperature Plasma Sintering: Bone Regeneration Applications

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Author(s):
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Gautam, Chandkiram [1, 2] ; Chakravarty, Dibyendu [3, 4] ; Gautam, Amarendra [1] ; Tiwary, Chandra Sekhar [2, 4] ; Woellner, Cristiano Francisco [2, 5] ; Mishra, Vijay Kumar [6] ; Ahmad, Naseer [6] ; Ozden, Sehmus [2] ; Jose, Sujin [7] ; Biradar, Santoshkumar [2] ; Vajtai, Robert [2] ; Trivedi, Ritu [6] ; Galvao, Douglas S. [5] ; Ajayan, Pulickel M. [2]
Total Authors: 14
Affiliation:
[1] Univ Lucknow, Dept Phys, Lucknow 226007, Uttar Pradesh - India
[2] Rice Univ, Dept Mat Sci & Nano Engn, Houston, TX 77005 - USA
[3] Int Adv Res Ctr Powder Met & New Mat ARCI, Hyderabad 500005, Telangana - India
[4] Indian Inst Technol, Dept Mat Sci & Engn, Gandhinagar, Gujarat - India
[5] Univ Estadual Campinas, UNICAMP, Appl Phys Dept, BR-13083859 Campinas, SP - Brazil
[6] CSIR Cent Drug Res Inst, Endocrinol Div, Lucknow 226031, Uttar Pradesh - India
[7] Madurai Kamaraj Univ, Sch Phys, Madurai 625021, Tamil Nadu - India
Total Affiliations: 7
Document type: Journal article
Source: ACS OMEGA; v. 3, n. 6, p. 6013-6021, JUN 2018.
Web of Science Citations: 5
Abstract

Recent advances and demands in biomedical applications drive a large amount of research to synthesize easily scalable low-density, high-strength, and wear-resistant biomaterials. The chemical inertness with low density combined with high strength makes h-BN one of the promising materials for such application. In this work, three-dimensional hexagonal boron nitride (h-BN) interconnected with boron trioxide (B2O3) was prepared by easily scalable and energy efficient spark plasma sintering (SPS) process. The composite structure shows significant densification (1.6-1.9 g/cm(3)) and high surface area (0.97-14.5 m(2)/g) at an extremely low SPS temperature of 250 degrees C. A high compressive strength of 291 MPa with a reasonably good wear resistance was obtained for the composite structure. The formation of strong covalent bonds between h-BN and B2O3 was formulated and established by molecular dynamics simulation. The composite showed significant effect on cell viability/proliferation. It shows a high mineralized nodule formation over the control, which suggests its use as a possible osteogenic agent in bone formation. (AU)

FAPESP's process: 16/12340-9 - Structural and mechanical properties of carbon-based foams
Grantee:Cristiano Francisco Woellner
Support type: Scholarships abroad - Research Internship - Post-doctor
FAPESP's process: 13/08293-7 - CCES - Center for Computational Engineering and Sciences
Grantee:Munir Salomao Skaf
Support type: Research Grants - Research, Innovation and Dissemination Centers - RIDC