Validation of the Modified Shuttle Test to Predict Peak Oxygen Uptake in Youth Asthma Patients Under Regular Treatment

Author(s)

Lanza, Fernanda C. ^[1] ; Reimberg, Mariana M. ^[1] ; Ritti-Dias, Raphael ^[1] ; Scalco, Rebeca S. ^[1] ; Wandalsen, Gustavo F. ^[2] ; Sole, Dirceu ^[2] ; van Brusse, Marco ^[3] ; Hulzebos, H. J. ^[3] ; Dal Corso, Simone ^[1] ; Takken, Tim ^[3]

Affiliation

^[1] Univ Nove Julho, Grad Program Rehabil Sci, Sao Paulo - Brazil

^[2] Univ Fed Sao Paulo, Pediat Dept, Sao Paulo - Brazil

^[3] Univ Med Ctr Utrecht, Child Dev & Exercise Ctr, Utrecht - Netherlands

• Document type: Journal article
• Source: FRONTIERS IN PHYSIOLOGY; v. 9, JUL 24 2018.
• Web of Science Citations: 1

Abstract

Background: Oxygen uptake (VO2) evaluations by cardiopulmonary exercise test is expensive and time-consuming. Estimating VO2 based on a field test would be an alternative. Objective: To develop and validate an equation to predict VO2peak based on the modified shuttle test (MST). Methods: Cross sectional study, with 97 children and adolescents with asthma. Participants were divided in two groups: the equation group (EG), to construct the equation model of VO2peak, and the cross-validation group (VG). Each subject performed the MST twice using a portable gas analyzer. The peak VO2peak during MST was used in the equation model. The patients' height, weight, gender, and distance walked (DW) during MST were tested as independent variables. Results: The final model {[}-0.457 + (gender x 0.139) + (weight x 0.025) + (DW x 0.002)] explained 87% of VO2peak variation. The VO2peak predicted was similar to VO2peak measured by gas analyzer (1.9 +/- 0.5 L/min and 2.0 +/- 0.5 L/min, respectively) (p = 0.67), and presented significant ICC 0.91 (IC95% 0.77 to 0.96); p < 0.001. The Bland-Altman analysis showed low bias (-0.15 L/min) and limits of agreement (-0.65 to 0.35 L/min). There was no difference in DW between EG (760 +/- 209 m) and VG (731 +/- 180 m), p = 0.51. Conclusion: The developed equation adequately predicts VO2peak in pediatric patients with asthma. (AU)

• FAPESP's process: 14/12040-0 - Physical capacity, peripheral muscle function, inflammation and quality of life in children and adolescents with asthma before and after pulmonary rehabilitation program
• Grantee: Fernanda de Cordoba Lanza
• Support Opportunities: Regular Research Grants
• FAPESP's process: 16/17553-0 - Relationship between lung function, functional capacity and daily physical activity in asthmatic children and adolescents
• Grantee: Rebeca Souza Scalco
• Support Opportunities: Scholarships in Brazil - Scientific Initiation