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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Contributions from the ovarian follicular environment to oocyte function

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Author(s):
del Collado, Maite [1] ; Andrade, Gabriella Mamede [1] ; Meirelles, Flavio Vieira [1] ; da Silveira, Juliano Coelho [1] ; Perecin, Felipe [1]
Total Authors: 5
Affiliation:
[1] Univ Sao Paulo, Fac Anim Sci & Food Engn, Dept Vet Med, Pirassununga, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: ANIMAL REPRODUCTION; v. 15, n. 3, p. 261-270, JUL-SEP 2018.
Web of Science Citations: 1
Abstract

The magnitude of oocyte's role for embryo development is categorical. This unique cell contains the machineries and cellular components necessary to remodel male and female chromatin, to sustain early development and to, ultimately, generate a complete and complex individual. However, to gain these competences before fertilization, the oocyte undergoes several morphological, cellular and molecular changes during its lifetime enclosed in the ovarian follicle. This review will briefly revisit how the oocyte orchestrate the follicular cells, and how molecules transit to the oocyte from the innermost (cumulus) and outermost (antrum and granulosa cells) layers surrounding the follicle-enclosed oocyte. Finally, we will discuss the interferences of in vitro culture conditions in the communication of the oocyte with its surrounding cells and the potential strategies to modulate these communication systems to increase oocyte competence. (AU)

FAPESP's process: 18/01431-9 - PI3K-Akt signaling pathway effect in oocyte maturation and early embryo development in cattle
Grantee:Gabriella Mamede Andrade
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 13/08135-2 - CTC - Center for Cell-Based Therapy
Grantee:Dimas Tadeu Covas
Support type: Research Grants - Research, Innovation and Dissemination Centers - RIDC
FAPESP's process: 14/21034-3 - Intra and intercellular routes during foliculogenesis and in vivo and in vitro oocyte maturation
Grantee:Felipe Perecin
Support type: Regular Research Grants
FAPESP's process: 14/22887-0 - Cell-secreted vesicles containing miRNAs modulate epigenetic changes during in vitro culture of bovine gametes and embryos
Grantee:Juliano Coelho da Silveira
Support type: Research Grants - Young Investigators Grants
FAPESP's process: 17/19825-0 - Mechanisms of oocyte lipid accumulation in obesity
Grantee:Maite Del Collado Barrondo
Support type: Scholarships in Brazil - Post-Doctorate