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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Genomic and epidemiological monitoring of yellow fever virus transmission potential

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Author(s):
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Faria, N. R. [1] ; Kraemer, M. U. G. [1, 2, 3] ; Hill, S. C. [1] ; de Jesus, J. Goes [4] ; Aguiar, R. S. [5] ; Iani, F. C. M. [6, 7] ; Xavier, J. [4] ; Quick, J. [8] ; du Plessis, L. [1] ; Dellicour, S. [9] ; Theze, J. [1] ; Carvalho, R. D. O. [6] ; Baele, G. [9] ; Wu, C. -H. [10] ; Silveira, P. P. [5] ; Arruda, M. B. [5] ; Pereira, M. A. [7] ; Pereira, G. C. [7] ; Lourenco, J. [1] ; Obolski, U. [1] ; Abade, L. [1, 11] ; Vasylyeva, T. I. [1] ; Giovanetti, M. [6, 4] ; Yi, D. [12] ; Weiss, D. J. [13] ; Wint, G. R. W. [1] ; Shearer, F. M. [13] ; Funk, S. [14] ; Nikolay, B. [15, 16, 17] ; Fonseca, V. [6, 18] ; Adelino, T. E. R. [7] ; Oliveira, M. A. A. [7] ; Silva, M. V. F. [7] ; Sacchetto, L. [6] ; Figueiredo, P. O. [6] ; Rezende, I. M. [6] ; Mello, E. M. [6] ; Said, R. F. C. [19] ; Santos, D. A. [19] ; Ferraz, M. L. [19] ; Brito, M. G. [19] ; Santana, L. F. [19] ; Menezes, M. T. [5] ; Brindeiro, R. M. [5] ; Tanuri, A. [5] ; dos Santos, F. C. P. [20] ; Cunha, M. S. [20] ; Nogueira, J. S. [20] ; Rocco, I. M. [20] ; da Costa, A. C. [21, 22] ; Komninakis, S. C. V. [23, 24] ; Azevedo, V. [6] ; Chieppe, A. O. [25] ; Araujo, E. S. M. [4] ; Mendonca, M. C. L. [4] ; dos Santos, C. C. [4] ; dos Santos, C. D. [4] ; Mares-Guia, A. M. [4] ; Nogueira, R. M. R. [4] ; Sequeira, P. C. [4] ; Abreu, R. G. [26] ; Garcia, M. H. O. [26] ; Abreu, A. L. [27] ; Okumoto, O. [27] ; Kroon, E. G. [6] ; de Albuquerque, C. F. C. [28] ; Lewandowski, K. [29] ; Pullan, S. T. [29] ; Carroll, M. [30] ; de Oliveira, T. [4, 18, 31] ; Sabino, E. C. [21, 22] ; Souza, R. P. [20] ; Suchard, M. A. [32, 33] ; Lemey, P. [9] ; Trindade, G. S. [6] ; Drumond, B. P. [6] ; Filippis, A. M. B. [4] ; Loman, N. J. [8] ; Cauchemez, S. [15, 16, 17] ; Alcantara, L. C. J. [6, 4] ; Pybus, O. G. [1]
Total Authors: 81
Affiliation:
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[1] Univ Oxford, Dept Zool, Oxford - England
[2] Boston Childrens Hosp, Computat Epidemiol Lab, Boston, MA - USA
[3] Harvard Med Sch, Dept Pediat, Boston, MA - USA
[4] Fiocruz MS, Inst Oswaldo Cruz, Lab Flavivirus, Rio De Janeiro - Brazil
[5] Univ Fed Rio de Janeiro, Inst Biol, Dept Genet, Mol Virol Lab, Rio De Janeiro - Brazil
[6] Univ Fed Minas Gerais, Inst Ciencias Biol, Belo Horizonte, MG - Brazil
[7] FUNED, Inst Octavio Magalhaes, Lab Cent Saude Publ, Belo Horizonte, MG - Brazil
[8] Univ Birmingham, Inst Microbiol & Infect, Birmingham, W Midlands - England
[9] Katholieke Univ Leuven, Dept Microbiol & Immunol, Rega Inst, Leuven - Belgium
[10] Univ Oxford, Dept Stat, Oxford - England
[11] Univ Oxford, Global Hlth Network, Oxford - England
[12] Harvard Univ, Dept Stat, Cambridge, MA 02138 - USA
[13] Univ Oxford, Nuffield Dept Med, Big Data Inst, Malaria Atlas Project, Oxford - England
[14] London Sch Hyg & Trop Med, Fac Epidemiol & Populat Hlth, London - England
[15] Inst Pasteur, Math Modelling Infect Dis, Paris - France
[16] Inst Pasteur, Ctr Bioinformat, Paris - France
[17] Inst Pasteur, CNRS, Genom Evolut Modelisat & Sante UMR2000, Paris - France
[18] Univ KwaZulu Natal, KwaZulu Natal Res Innovat & Sequencing Platform K, Sch Lab Med & Med Sci, Durban - South Africa
[19] Secretaria Estado Saude Minas Gerais, Belo Horizonte, MG - Brazil
[20] Adolfo Lutz Inst, Nucleo Doencas Transmissao Vetorial, Sao Paulo - Brazil
[21] Univ Sao Paulo, Fac Med, Sao Paulo - Brazil
[22] Univ Sao Paulo, Inst Trop Med, Sao Paulo - Brazil
[23] Univ Fed Sao Paulo, Retrovirol Lab, Sao Paulo - Brazil
[24] Sch Med ABC FMABC, Clin Immunol Lab, Santo Andre, SP - Brazil
[25] Coordenacao Vigilancia Epidemiol Estado Rio de Ja, Rio De Janeiro - Brazil
[26] Minist Saude, Dept Vigilancia Doencas Transmissiveis, Secretaria Vigilancia Saude, Brasilia, DF - Brazil
[27] Minist Saude, Secretaria Vigilancia Saude, Coordenacao Geral Labs Saude Publ, Brasilia, DF - Brazil
[28] OMS, OPAS, Brasilia, DF - Brazil
[29] Publ Hlth England, Natl Infect Serv, Salisbury, Wilts - England
[30] Publ Hlth England, NIHR HPRU Emerging & Zoonot Infect, London - England
[31] Ctr AIDS Programme Res South Africa CAPRISA, Durban - South Africa
[32] Univ Calif Los Angeles, Dept Biostat, Fielding Sch Publ Hlth, Los Angeles, CA - USA
[33] Univ Calif Los Angeles, David Geffen Sch Med, Dept Biomath & Human Genet, Los Angeles, CA 90095 - USA
Total Affiliations: 33
Document type: Journal article
Source: Science; v. 361, n. 6405, p. 894+, AUG 31 2018.
Web of Science Citations: 42
Abstract

The yellow fever virus (YFV) epidemic in Brazil is the largest in decades. The recent discovery of YFV in Brazilian Aedes species mosquitos highlights a need to monitor the risk of reestablishment of urban YFV transmission in the Americas. We use a suite of epidemiological, spatial, and genomic approaches to characterize YFV transmission. We show that the age and sex distribution of human cases is characteristic of sylvatic transmission. Analysis of YFV cases combined with genomes generated locally reveals an early phase of sylvatic YFV transmission and spatial expansion toward previously YFV-free areas, followed by a rise in viral spillover to humans in late 2016. Our results establish a framework for monitoring YFV transmission in real time that will contribute to a global strategy to eliminate future YFV epidemics. (AU)

FAPESP's process: 17/00021-9 - Viral metagenomics to track, explain and predict the transmission and spatiotemporal spread of Dengue and Chikungunya viruses in Brazil
Grantee:Antonio Charlys da Costa
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 16/01735-2 - Viral metagenomics to track, explain and predict the transmission and spatiotemporal spread of Dengue and Chikungunya viruses in Brazil
Grantee:Ester Cerdeira Sabino
Support Opportunities: Regular Research Grants