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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose

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Author(s):
Elias, Luciana M. [1] ; Fortlzamp, Diana [1] ; Sartori, Sergio B. [1] ; Ferreira, Marilia C. [1] ; Gomes, Luiz H. [1] ; Azevedo, Joao L. [2] ; Montoya, V, Quimi ; Rodrigues, Andre [3] ; Ferreira, Antonio G. [4] ; Lira, Simone P. [1]
Total Authors: 10
Affiliation:
[1] Univ Sao Paulo, Dept Ciencias Exatas, Escola Super Agr Luiz de Queiroz, Piracicaba, SP - Brazil
[2] Univ Sao Paulo, Dept Genet, Escola Super Agr Luiz de Queiroz, Piracicaba, SP - Brazil
[3] Montoya, Quimi, V, Univ Estadual Paulista, Inst Biociencias, Dept Bioquim & Microbiol, Rio Claro, SP - Brazil
[4] Univ Fed Sao Carlos, Dept Quim, Sao Carlos, SP - Brazil
Total Affiliations: 4
Document type: Journal article
Source: Brazilian Journal of Microbiology; v. 49, n. 4, p. 840-847, OCT-DEC 2018.
Web of Science Citations: 1
Abstract

Anthracnose is a crop disease usually caused by fungi in the genus Colletotrichum or Gloeosporium. These are considered one of the main pathogens, causing significant economic losses, such as in peppers and guarana. The current forms of control include the use of resistant cultivars, sanitary pruning and fungicides. However, even with the use of some methods of controlling these cultures, the crops are not free of anthracnose. Additionally, excessive application of fungicides increases the resistance of pathogens to agrochemicals and cause harm to human health and the environment. In order to find natural antifungal agents against guarana anthracnose, endophytic fungi were isolated from Amazon guarana. The compounds piliformic acid and cytochalasin D were isolated by chromatographic techniques from two Xylaria spp., guided by assays with Colletotrichum gloeosporioides. The isolated compounds were identified by spectrometric techniques, as NMR and mass spectrometry. This is the first report that piliformic acid and cytochalasin D have antifungal activity against C. gloeosporioides with MIC 2.92 and 2.46 mu mol mL(-1) respectively. Captan and difenocona-zole were included as positive controls (MIC 16.63 and 0.02 mu mol mL(-1), respectively). Thus, Xylaria species presented a biotechnological potential and production of different active compounds which might be promising against anthracnose disease. (C) 2018 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda. (AU)

FAPESP's process: 13/50228-8 - Biodiversity components, and its metabolic characters, of Brazilian Islands
Grantee:Roberto Gomes de Souza Berlinck
Support type: BIOTA-FAPESP Program - Thematic Grants
FAPESP's process: 14/15760-3 - Biotechnological potential of secondary metabolites from plants and endophytic fungi
Grantee:Simone Possedente de Lira
Support type: Regular Research Grants
FAPESP's process: 12/02000-5 - Bioprospecting endophytic fungi isolated from Amazon guarana tree
Grantee:Luciana Mecatti Elias
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 14/05940-4 - Chemical and biological study of two strains of endophytic fungi isolated from guarana leaves of Amazonas
Grantee:Marília Capellaro Ferreira
Support type: Scholarships in Brazil - Scientific Initiation