Palladium orthometallated complexes containing acetophenoneoxime: Synthesis, crystal structures and hirshfeld surface analysis

Author(s)

Bozza, Gabriela F. ^[1] ; de Farias, Renan L. ^[1] ; de Souza, Ronan F. F. ^[1] ; Rocha, V, Fillipe ; Barra, V, Carolina ; Deflon, Victor M. ^[2] ; de Almeida, Eduardo T. ^[3] ; Mauro, Antonio E. ^[1] ; Netto, Adelino V. G. ^[1]

Affiliation

^[1] Univ Estadual Paulista, UNESP, Inst Chem, BR-14800060 Araraquara, SP - Brazil

^[2] Univ Sao Paulo, Inst Quim Sao Carlos, Sao Carlos, SP - Brazil

^[3] UNIFAL MG Univ Fed Alfenas, Inst Quim, Alfenas, MG - Brazil

• Document type: Journal article
• Source: Journal of Molecular Structure; v. 1175, p. 195-207, JAN 5 2019.
• Web of Science Citations: 3

Abstract

The bridge-splitting reaction between {[}Pd(C-2,N-aphox)(mu-Cl)](2) and phosphines (L), in a 1:2 ratio, yielded neutral mononuclear cyclopalladated compounds of the type {[}PdCl(C-2,N-aphox)(L)] faphox = aceto-phenoneoxime; L= triphenylphosphine (1), tris(4-fluorophenyl)phosphine (2), tri-cyclohexylphosphine (3), diphenyl(p-toluyl)phosphine (4), tris-(4-methoxyphenyl)phosphine (5) and tri(p-toluyl)phosphine (6)). The compounds were characterized by elemental analyses, IR and H-1-, C-13[H-1)- and (31)p[H-1]-NMR spectroscopies. The crystal and molecular structures of 1-5 were determined by single-crystal X-ray diffraction. After that, the Hirshfeld surface calculations were carried out to explore the nature and major contributions of different intermolecular contacts towards crystal packing stability. (C) 2018 Elsevier B.V. All rights reserved. (AU)

• FAPESP's process: 12/15486-3 - Pd(II) compounds: synthesis, cytotoxicity, and DNA binding studies
• Grantee: Regina Celia Galvao Frem
• Support Opportunities: Regular Research Grants
• FAPESP's process: 16/17711-5 - INVESTIGATION OF THE ANTITUMOR POTENTIAL OF PALLADIUM(II) COMPOUNDS CONTAINING ORTHOMETALLATED OR N,S-DONOR LIGANDS
• Grantee: Adelino Vieira de Godoy Netto
• Support Opportunities: Regular Research Grants
• FAPESP's process: 14/11340-0 - NEW Pd(II) ORGANOMETALLIC COMPLEXES: INVESTIGATION OF THEIR POTENTIAL AS CATHEPSIN B INHIBITORS
• Grantee: Carolina Valério Barra Rocha
• Support Opportunities: Scholarships in Brazil - Post-Doctoral