| Full text | |
| Author(s): |
Marrara, Kamilla Tays
[1, 2]
;
Pires Di Lorenzo, Valeria Amorim
[3]
;
Jaenisch, Rodrigo B.
[1]
;
Cabiddu, Ramona
[1]
;
Sato, Tatiana de Oliveira
[4]
;
Mendes, Renata Goncalves
[1]
;
Oliveira, Claudio R.
[5]
;
Costa, Dirceu
[6]
;
Borghi-Silva, Audrey
[1]
Total Authors: 9
|
| Affiliation: | [1] Univ Fed Sao Carlos, Cardiopulm Physiotherapy Lab, Sao Carlos, SP - Brazil
[2] Cent Univ Sao Paulo, Sao Carlos, SP - Brazil
[3] Univ Fed Sao Carlos, Res Lab Spirometry & Resp Physiotherapy, Sao Carlos, SP - Brazil
[4] Univ Fed Sao Carlos, Prevent Physiotherapy & Ergon Lab, Sao Carlos, SP - Brazil
[5] Univ Fed Sao Carlos, Dept Med, Sao Carlos, SP - Brazil
[6] Univ Nove Julho, Sao Paulo - Brazil
Total Affiliations: 6
|
| Document type: | Journal article |
| Source: | Respiratory Care; v. 63, n. 11, p. 1388-1398, NOV 1 2018. |
| Web of Science Citations: | 1 |
| Abstract | |
BACKGROUND: The primary objective of this study was to investigate whether noninvasive ventilation (NIV) can positively affect exercise capacity, maximum oxygen uptake (V-O2), and symptoms after a 6-week physical training program for subjects with moderate to very severe COPD. METHODS: 47 subjects with COPD who were enrolled in a physical training program were randomized to either physical training alone or NIV + physical training (NIV-Physical training). Physical training consisted of dynamic aerobic exercises on a treadmill 3 times/week for 6 weeks, for a total of 18 sessions. NIV was titrated according to the subject's tolerance at rest and during exercise. Assessments included physiological responses and symptoms at the incremental cardio-pulmonary exercise test peak and during submaximal exercise on a treadmill, 6-min walk distance, maximum inspiratory (P-IMAX) and expiratory pressure (P-EMAX), BODE index, and health-related quality of life. RESULTS: 43 subjects completed the 6-week physical training program. Both groups improved 6-min walk distance, P-IMAX, BODE index, and quality of life, and no differences were found between groups. However, significant improvements were observed for subjects in the NIV-Physical training group with regard to P(EMAX, )maximum V-O2, maximum metabolic equivalents, circulatory power, and maximum S-pO2. CONCLUSIONS: A 6-week physical training program alone can improve tolerance for exercise and quality of life, in addition to reducing the risk of mortality. However, NIV associated with a physical training program was shown to have an additive beneficial effect on powerful prognostic markers (maximum V(O2 )and circulatory power) and to reduce symptoms and improve oxygen saturation in subjects with moderate to very severe COPD. (AU) | |
| FAPESP's process: | 09/01842-0 - Analysis of central and peripheral muscle metabolism and adjustments on dynamic versus resistance exercise in coronary arterial disease patients: effects of resistance physical training program based on anaerobic threshold by different methodologies |
| Grantee: | Audrey Borghi Silva |
| Support Opportunities: | Research Grants - Young Investigators Grants |