| Full text | |
| Author(s): Show less - |
de Moura, Luciana Monteiro
[1, 2, 3]
;
Cogo-Moreira, Hugo
[3]
;
Brandao de Avila, Clara Regina
[4]
;
Pan, Pedro Mario
[2]
;
Gadelha, Ary
[2]
;
Moriyama, Tais
[2]
;
Del Aquilla, Marco Antonio
[2]
;
Hoexter, Marcelo
[2]
;
Salum, Giovanni Abrahao
[5]
;
Picon, Felipe Almeida
[5]
;
Anes, Mauricio
[5]
;
Mercadante, Marcos Tomanik
[2]
;
Lacerda, Acioly
[2]
;
Amaro Jr, Edson
;
Miguel, Euripedes Constantino
[6]
;
Rohde, Luis Augusto
[5]
;
Bressan, Rodrigo Affonseca
[2, 3]
;
McGuire, Philip
[1]
;
Sato, Joao Ricardo
[7]
;
Mari, Jair de Jesus
[3]
;
Jackowski, Andrea Parolin
[2, 3]
Total Authors: 21
|
| Affiliation: | [1] Kings Coll London, Inst Psychiat, London - England
[2] Univ Fed Sao Paulo, UNIFESP, Interdisciplinary Lab Clin Neurosci LiNC, Sao Paulo - Brazil
[3] Univ Fed Sao Paulo, Dept Psychiat, Rua Pedro Toledo 669, 3 Andar, BR-04039032 Sao Paulo - Brazil
[4] Univ Fed Sao Paulo, Dept Language Speech & Hearing Pathol, Sao Paulo - Brazil
[5] Fed Univ Rio Grande, Dept Psychiat, Porto Alegre, RS - Brazil
[6] Univ Sao Paulo, Sao Paulo Med Sch, Dept Psychiat, Sao Paulo - Brazil
[7] Univ Fed ABC, Ctr Math Computat & Cognit, Santo Andre - Brazil
Total Affiliations: 7
|
| Document type: | Journal article |
| Source: | BRAIN CONNECTIVITY; v. 6, n. 7, p. 519-523, SEP 2016. |
| Web of Science Citations: | 2 |
| Abstract | |
Diffusion tensor imaging (DTI) studies showed that microstructural alterations are correlated to reading skills. In this study, we aim to investigate white matter microstructure of a group of Portuguese speakers with poor reading level, using different parameters of DTI. To perform this analysis, we selected children ranging from 8 to 12 years of age, poor readers (n = 17) and good readers (n = 23), evaluated in the word-level ability based on a Latent Class Analysis (LCA) of Academic Performance Test (TDE). Poor readers exhibited significant fractional anisotropy (FA) reductions in many tracts of both hemispheres, but small and restricted clusters of increased radial diffusivity (RD) in the left hemisphere. Spatial coherence of fibers might be the main source of differences, as changes in FA were not similarly accompanied in terms of extension by changes in RD. Widespread structural alterations in the white matter could prevent good reading ability at word level, which is consistent with recent studies demonstrating the involvement of multiple cortical regions and white matter tracts in reading disabilities. (AU) | |
| FAPESP's process: | 13/10498-6 - Machine learning in neuroimaging: development of methods and clinical applications in psychiatric disorders |
| Grantee: | João Ricardo Sato |
| Support Opportunities: | Regular Research Grants |