Relationship of evening meal with sleep quality in obese individuals with obstructive sleep apnea

Author(s)

de Melo, Camila Maria ^{[1, 2]} ; del Re, Mariana Pantaleao ^[1] ; Lucio dos Santos Quaresma, Marcus Vinicius ^[3] ; Moreira Antunes, Hanna Karen ^[3] ; Togeiro, Sonia Maria ^[1] ; Lima Ribeiro, Sandra Maria ^{[4, 5, 2]} ; Tufik, Sergio ^[1] ; de Mello, Marco Tulio ^{[6, 1]}

Affiliation

^[1] Univ Fed Sao Paulo, Dept Psychobiol, Rua Botucatu 862, 3R-04023062 Sao Paulo - Brazil

^[2] Univ Sao Paulo, Interunits Program Human Nutr, Sao Paulo - Brazil

^[3] Univ Fed Sao Paulo, Dept Biosci, Sao Paulo - Brazil

^[4] Univ Sao Paulo, Sch Arts Sci & Humanities, Sao Paulo - Brazil

^[5] Univ Sao Paulo, Sch Publ Hlth, Sao Paulo - Brazil

^[6] Univ Fed Minas Gerais, Sch Phys Educ Physiotherapy & Occupat Therapy, Belo Horizonte, MG - Brazil

• Document type: Journal article
• Source: CLINICAL NUTRITION ESPEN; v. 29, p. 231-236, FEB 2019.
• Web of Science Citations: 0

Abstract

Purpose: To determine the relationship between habitual food intake, resting energy expenditure and sleep pattern in obstructive sleep apnea (OSA) patients. Methods: Forty-five OSA obese males were included in the study. All participants were submitted to nocturnal polysomnography, body composition measurements by plethysmography, resting energy expenditure (REE) analysis by indirect calorimetry and they filled in a 3-day food record. Results: No differences in body composition, REE and food intake were found between the moderate and severe OSA groups. A trend towards higher energy intake in the severe OSA group was observed, compared to the moderate group (p = 0.08). Significant associations between apnea-hypopnea index (AHI) with body weight, body mass index (BMI) and resting energy expenditure (REE) were found. Higher food intake in the evening period was positively correlated with sleep stage NREM1, arousal index, and AHI and negatively correlated with sleep stage NREM3 and sleep efficiency. A multivariate linear regression showed energy intake at breakfast to be a significant negative predictor of AHI; protein intake (g/kg) showed a positive association, while energy intake at breakfast and at dinner were negative predictors of sleep efficiency; and energy intake at dinner was a negative predictor of stage NREM1 sleep. Conclusions: We conclude that higher amounts of food intake during the evening period may diminish sleep quality in moderate and severe sleep apnea patients. In addition, despite observing no differences between OSA severity groups, a moderate correlation between REE and sleep quality and OSA exists. (C) 2018 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved. (AU)

• FAPESP's process: 12/09700-2 - Physiological and immunological effects of sleep restriction on three approaches: experimental sleep restriction, shift work and sleep disorders
• Grantee: Marco Túlio de Mello
• Support Opportunities: Regular Research Grants