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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Home-based and informal work exposes the families to high levels of potentially toxic elements

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Sacone da Silva Ferrreira, Ana Paula [1] ; Pereira, Elizeu Chiodi [1] ; Salles, Fernanda Junqueira [1] ; da Silva, Fabio Ferreira [2] ; Batista, Bruno Lemos [2] ; Handakas, Evangelos [3] ; Kaneshiro Olympio, Kelly Polido [1]
Total Authors: 7
[1] Univ Sao Paulo, Dept Environm Hlth, Sch Publ Hlth, Av Dr Arnaldo 715, BR-01246904 Sao Paulo, SP - Brazil
[2] Fed Univ ABC, Ctr Nat & Human Sci, Ave Estados 5001, BR-09210580 Santo Andre, SP - Brazil
[3] Imperial Coll London, Dept Med Computat & Med, London - England
Total Affiliations: 3
Document type: Journal article
Source: Chemosphere; v. 218, p. 319-327, MAR 2019.
Web of Science Citations: 0

The city of Limeira presents a relevant productive chain of jewelry and fashion jewelry, including a scenario of outsourcing informal home practices. It is highly complex to understand the potentially toxic elements (PTE: Cr, Mn, Ni, Cu, Zn, As, Cd, Sn, Sb, Hg, and Pb) exposures of the workers because this productive chain encompasses households. This study aimed to investigate the associations between blood PTE levels and informal work in the home environment. Fifty-two families divided into Exposed group (n = 112) and Control group (n = 53) were included. Families' blood (n = 165) and welder's breathing zone air samples (n = 9) were collected and PTEs concentrations were determined by ICP-MS. Questionnaires were applied to collect sociodemographic information and workplace details. Principal component analysis, Mann-Whitney test, cluster and a logistic regression analysis based on environment-wide association studies (EWAS) were carried out. Ni, Cu, Zn, Cd and Pb concentrations in the air samples were higher than occupational guidelines. Eighty percent of the workers were female, and 43.5% of those females then worked as welder. A significant difference was found for Pb concentration between the exposed and control group (p < 0.0001) and between sexes (p = 0.0046). For Cu (p < 0.0001) and Sb (p = 0.0434), differences were found between the sexes. The receiver operating characteristic of the EWAS was 0.80, providing evidence of a potential model to associate exposure levels and occupational factors. PTEs concentrations in the air samples raised concerns, particularly for children, who were in the same exposure scenario. Inadequate work conditions were observed in the houses, revealing the need of public actions to protect these families. (C) 2018 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 16/11087-8 - From exposome up to Regulatory Toxicology: a thematic study on potentially toxic elements (PTEs) exposure of families inserted in informal productive arrangement in the jewelry and fashion jewelry chain from Limeira, SP
Grantee:Kelly Polido Kaneshiro Olympio
Support type: Regular Research Grants
FAPESP's process: 16/07457-4 - Families inserted in Local Productive Arrangement of the productive chain of jewelry and fashion jewelry from Limeira, SP: the occupational exposure to chemical contaminants in home setting
Grantee:Ana Paula Sacone da Silva Ferreira
Support type: Scholarships in Brazil - Master
FAPESP's process: 16/10060-9 - Multi-user equipment (MUE) approved in Grant FAPESP project 2014/05151-0: inductively coupled plasma mass spectrometer hyphenated to an high performance liquid chromatography (HPLC-ICP-MS)
Grantee:Bruno Lemos Batista
Support type: Multi-user Equipment Program
FAPESP's process: 17/15797-2 - Understanding the exposome approach: from the concept to the applications in public health
Grantee:Ana Paula Sacone da Silva Ferreira
Support type: Scholarships abroad - Research Internship - Master's degree
FAPESP's process: 17/14392-9 - Living and working conditions of youths inserted in the informal and household productive arrangement of jewelry and fashion jewelry from the exposome perspective
Grantee:Elizeu Chiodi Pereira
Support type: Scholarships in Brazil - Scientific Initiation