Frequency of anti- Toxoplasma gondii IgA, IgM, and IgG antibodies in high-risk pregnancies, in Brazil

Author(s)

Fernando Henrique Antunes Murata ; Marina Neves Ferreira ; Natália Sahyoun Camargo ^[3] ; Gabriela Soria Santos ^[4] ; Lígia Cosentino Junqueira Franco Spegiorin ; Aparecida Perpétuo Silveira-Carvalho ; Vera Lucia Pereira-Chioccola ^[7] ; Luiz Carlos de Mattos ; Cinara Cássia Brandão de Mattos

• Document type: Journal article
• Source: Revista da Sociedade Brasileira de Medicina Tropical; v. 49, n. 4, p. 512-514, 2016-08-00.

Abstract

Abstract: INTRODUCTION Toxoplasmosis during pregnancy can be severe; thus, it is essential to diagnose the disease via serological tests. METHODS An enzyme-linked immunosorbent assay (ELISA) was used to investigate anti-Toxoplasma gondii immunoglobulin A (IgA), M (IgM) and G (IgG) antibodies in 62 high-risk pregnant women. RESULTS Forty-three (69.4%) women were positive for IgA, 31 (50%) for IgG, and 57 (91.9%) for IgM; 4 (6,5%) were positive for IgA but negative for IgM; 10 (16.1%) were negative for IgA and IgM but positive for IgG. CONCLUSIONS Testing for these antibodies can help diagnose infection in pregnant women, thereby contributing to clinical management. (AU)

• FAPESP's process: 12/07716-9 - Serological and molecular investigation of Toxoplasma gondii in blood donors
• Grantee: Luiz Carlos de Mattos
• Support Opportunities: Regular Research Grants
• FAPESP's process: 14/01706-7 - Genotypic characterization of Toxoplasma gondii in samples of pregnant women in the northwest region of the state of São Paulo
• Grantee: Marina Neves Ferreira
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 13/15879-8 - Toxoplasma gondii infection: serological and molecular characterization in patients attended in public health service (SUS)
• Grantee: Fernando Henrique Antunes Murata
• Support Opportunities: Scholarships in Brazil - Master