Advanced search
Start date
Betweenand
Related content
(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

A didactic chemometrics experiment for design of experiments (doe): evaluation of experimental conditions in the spectrophotometric determination of iron II with o-phenanthroline. a tutorial, part III

Full text
Author(s):
Márcia Cristina Breitkreitz [1] ; André Marcelo de Souza [2] ; Ronei Jesus Poppi [3]
Total Authors: 3
Affiliation:
[1] Universidade Estadual de Campinas. Instituto de Química. Departamento de Química Analítica - Brasil
[2] Universidade Estadual de Campinas. Instituto de Química. Departamento de Química Analítica - Brasil
[3] Universidade Estadual de Campinas. Instituto de Química. Departamento de Química Analítica - Brasil
Total Affiliations: 3
Document type: Journal article
Source: Química Nova; v. 37, n. 3, p. 564-573, 2014-06-00.
Abstract

The objective of this manuscript is to describe a practical experiment that can be employed for teaching concepts related to design of experiments using Matlab or Octave computing environment to beginners, undergraduate and graduate students. The classical experiment for determination of Fe (II) using o-phenanthroline was selected because it is easy to understand, and all the required materials are readily available in most analytical laboratories. The approach used in this tutorial is divided in two steps: first, the students are introduced to the concept of multivariate effects, how to calculate and interpret them, and the construction and evaluation of a linear model to describe the experimental domain by using a 2³ factorial design. Second, an extension of the factorial design by adding axial points is described, thereby, providing a central composite design. The quadratic model is then introduced and used to build the response surface. (AU)