| Full text | |
| Author(s): |
Bernardino, Pedro N.
[1]
;
Martins, Aline F. A.
[1]
;
Barbosa, Jose D.
[2]
;
Schild, Ana L.
[3]
;
Dame, Maria Cecilia F.
[4]
;
Borges, Alexandre S.
[1]
;
Oliveira, Jose P.
[1]
Total Authors: 7
|
| Affiliation: | [1] Univ Estadual Paulista, Dept Clin Vet, Fac Med Vet & Zootecnia, UNESP, Rua Prof Doutor Walter Mauricio Correa S-N, BR-18618681 Botucatu, SP - Brazil
[2] Univ Fed UFPA, Fac Med Vet, Inst Med Vet, Campus Castanhal, Rodovia BR 316 Km 61, BR-68741740 Castanhal, PA - Brazil
[3] Univ Fed Pelotas, Fac Vet, Lab Reg Diagnost, Rua Gomes Carneiro 1, BR-96010610 Pelotas, RS - Brazil
[4] Embrapa Clima Temperado, Campus Univ S-N, BR-96010971 Capao Do Leao, RS - Brazil
Total Affiliations: 4
|
| Document type: | Journal article |
| Source: | Pesquisa Veterinária Brasileira; v. 39, n. 3, p. 175-178, MAR 2019. |
| Web of Science Citations: | 0 |
| Abstract | |
ABSTRACT: Albinism is a genetic disease characterized by deficient melanin production making affected animals more susceptible to skin problems, negatively influencing production systems of the same. In buffalo, a nonsense mutation (c.1431G>A) in the tyrosinase gene was already described, which is responsible for the oculocutaneous albinism buffalo phenotype. However, prevalence studies have never been performed for this anomaly in Brazil. Therefore, the objective of this study was to investigate this mutation in buffalo herd in Brazil. Of the 315 buffalo tested with no albinism phenotype evident, 11 (3.5%) were heterozygous for the mutation and none were mutated homozygous, showing the existence of the albinism gene in buffalo production herds and proving the importance of prevalence studies for hereditary diseases in order to prevent the dissemination of these same genes and their negative productivity consequences. (AU) | |
| FAPESP's process: | 15/23569-4 - Detection of the mutations responsibles for albinism and congenital miotonia in buffaloes (Bubalus bubalis) |
| Grantee: | Pedro Negri Bernardino |
| Support Opportunities: | Scholarships in Brazil - Scientific Initiation |