| Full text | |
| Author(s): |
Aquino, Amanda J.
[1]
;
Alves, Thayana da C.
[2]
;
Oliveira, V, Regina
;
Ferreira, Antonio G.
[2]
;
Cass, Quezia B.
[3]
Total Authors: 5
|
| Affiliation: | [1] Univ Fed Sao Carlos, Chem Dept, Nucleo Pesquisa Cromatog Separare, BR-13565905 Sao Carlos, SP - Brazil
[2] Univ Fed Sao Carlos, Chem Dept, Lab Nucl Magnet Resonance, Sao Carlos, SP - Brazil
[3] Oliveira, Regina, V, Univ Fed Sao Carlos, Chem Dept, Nucleo Pesquisa Cromatog Separare, BR-13565905 Sao Carlos, SP - Brazil
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | INDUSTRIAL CROPS AND PRODUCTS; v. 132, p. 59-68, JUN 2019. |
| Web of Science Citations: | 1 |
| Abstract | |
The genus Bauhinia belongs to the family Fabaceae and comprises about 18,000 known species in the world. In Brazil, approximately more than 60 native species of Bauhinia are found. Bauhinia leaves tea infusion or other preparations have been widely used in the Brazilian popular medicine for treatment of several illnesses. Therefore, this work aims to a better understanding of Bauhinia longifolia to provide a valuable database for its quality control, pharmacological and toxicological studies. For the chemical analysis, a liquid chromatography-high resolution quadrupole-time of flight mass spectro-meter method was applied to evaluate the chemical profile of Bauhinia longifolia ethanolic leaves extracts, allowing for the identification of 75 compounds comprising chemical classes of phenolic acids, proanthocyanidins, and O-glycosides flavonoids. Most polyphenols were identified for the first time in this specie. In addition, six compounds were isolated and fully identified by liquid chromatography hyphenate to solid phase extraction and nuclear magnetic resonance. Herein, myricitrin, juglanin, afzelin, and bauhiniastatin 2 are reported for the first time for Bauhinia longifolia. Bauhiniastatin 2 has been reported to display anticancer properties towards several cancer cell lines. The chemical profile herein described for the ethanolic leaves extract of Bauhinia longifolia provided essential information of this Brazilian native species. (AU) | |
| FAPESP's process: | 13/01710-1 - Enzyme ligand: new models of screening |
| Grantee: | Quezia Bezerra Cass |
| Support Opportunities: | Research Projects - Thematic Grants |