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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Genomic characterization and comparative analysis of Leptospira kirschneri serogroup Grippotyphosa UC5/2011, a strain isolated after mare abortion: Implications for genital animal leptospirosis

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Author(s):
Jaeger, Lauren H. [1, 2] ; Moreno, Luisa Z. [3] ; Kremer, Frederico S. [4] ; Dellagostin, Odir A. [4] ; Moreno, Andrea M. [3] ; Lilenbaum, Walter [1]
Total Authors: 6
Affiliation:
[1] Univ Fed Fluminense, Dept Microbiol & Parasitol, Lab Bacteriol Vet, Rua Prof Hernani Melo 101, BR-24210130 Niteroi, RJ - Brazil
[2] Univ Fed Juiz De Fora, Fac Farm, Rua Jose Lourenco Kelmer S-N, BR-36036900 Juiz De Fora - Brazil
[3] Univ Sao Paulo, Fac Med Vet & Zootecnia, Lab Epidemiol Mol & Resistencia Antimicrobianos, Ave Prof Orlando Marques de Paiva 87, BR-05508010 Sao Paulo - Brazil
[4] Univ Fed Pelotas, Nucleo Biotecnol, Ctr Desenvolvimento Tecnol, Rua Gomes Carneiro 1, BR-96010610 Pelotas - Brazil
Total Affiliations: 4
Document type: Journal article
Source: COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES; v. 64, p. 7-9, JUN 2019.
Web of Science Citations: 0
Abstract

The genome of a Brazilian strain of Leptospira kirschneri serogroup Grippotyphosa isolated from a mare post-abortion was sequenced and analyzed. High symmetrical identity and few structural differences were found when compared with a European strain of the same serogroup, L. kirschneri serovar Valbuzzi strain 200702274. Genes associated with virulence and antimicrobial resistance were found. Knowledge of the virulence evolution of Leptospira remains limited, especially in diseases of the reproductive sphere. We highlight the importance of virulence studies in the sphere of genital leptospirosis. (AU)

FAPESP's process: 13/17136-2 - Characterization of Leptospira strains isolated in Brazil by pulsed field gel electrophoresis (PFGE) typing and comparative genomic analysis.
Grantee:Luisa Zanolli Moreno
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 11/18290-0 - Characterization of Leptospira strains isolated in Brazil through multiloccus sequence typing (MLST)
Grantee:Andrea Micke Moreno
Support Opportunities: Regular Research Grants