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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Urethanes PDMS-based: Functional hybrid coatings for metallic dental implants

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Rossi de Aguiar, Kelen M. F. [1, 2, 3] ; Nascimento, V, Matheus ; Faccioni, Juliano L. [4, 5] ; Noeske, Paul-Ludwig M. [4] ; Gaetjen, Linda [4] ; Rischka, Klaus [4] ; Rodrigues-Filho, Ubirajara P. [2]
Total Authors: 7
[1] Fraunhofer Inst Mfg Technol & Adv Mat IFAM, Bremen - Germany
[2] Univ Sao Paulo, Inst Chem Sao Carlos, Grp Chem Hybrid & Inorgan Mat GQMATHI, Sao Carlos, SP - Brazil
[3] Univ Tecnol Fed Parana, Polymers & Nanostruct Res Grp GPAN, Toledo - Brazil
[4] Nascimento, Matheus, V, Fraunhofer Inst Mfg Technol & Adv Mat IFAM, Bremen - Germany
[5] Fed Univ Rio Grande do Sul Labsinal UFRGS, Porto Alegre, RS - Brazil
Total Affiliations: 5
Document type: Journal article
Source: Applied Surface Science; v. 484, p. 1128-1140, AUG 1 2019.
Web of Science Citations: 1

In this study, we propose new polymeric coatings for metallic implants that impart biocompatibility and antibacterial features to such surfaces. The starting material, poly(cyclic carbonate)-polydimethylsiloxane, was prepared from carbon dioxide fixation and then sequentially reacted by aminolysis with an organoaminosilane, affording the formation of an urethanic polydimethylsiloxane-based material. Finally, a hybrid coating was obtained by performing a sol-gel process on the metallic surfaces, catalyzed by phosphotungstic acid. We provide evidence that due to the polydimethylsiloxane segments governing the surface termination, the hybrid coatings show a hydrophobic character. Furthermore, due the presence of phosphotungstic acid in the upper surface, the adhesion of Gram-positive and Gram-negative bacteria is suppressed in 4 h of contact with aqueous bacterial cultures. In addition, the coatings presented a > 70% cytocompatibility besides a low cytotoxicity, making them interesting candidates as biocompatible materials and an alternative to avoiding the biofilm associated with bacterial infections. (AU)

FAPESP's process: 11/08120-0 - Nanostructured films: on the influence of the architecture on Photoactivity properties of films with phosphotungstate and nanoparticles
Grantee:Ubirajara Pereira Rodrigues Filho
Support type: Regular Research Grants
FAPESP's process: 13/05279-3 - Poly(dimethylsiloxane) based segmented urethanes biomimetic adhesives Based on CO2 fixation
Grantee:Kelen Menezes Flores Rossi de Aguiar
Support type: Scholarships abroad - Research Internship - Doctorate
FAPESP's process: 11/06019-0 - CO2 uptake and synthesis of POLYURETANES-POLYSILICONE co-polymers as additives incorporated in ormosils: use on bioactive and ion conducting films
Grantee:Kelen Menezes Flores Rossi de Aguiar
Support type: Scholarships in Brazil - Doctorate