| Full text | |
| Author(s): |
Rossi de Aguiar, Kelen M. F.
[1, 2, 3]
;
Nascimento, V, Matheus
;
Faccioni, Juliano L.
[4, 5]
;
Noeske, Paul-Ludwig M.
[4]
;
Gaetjen, Linda
[4]
;
Rischka, Klaus
[4]
;
Rodrigues-Filho, Ubirajara P.
[2]
Total Authors: 7
|
| Affiliation: | [1] Fraunhofer Inst Mfg Technol & Adv Mat IFAM, Bremen - Germany
[2] Univ Sao Paulo, Inst Chem Sao Carlos, Grp Chem Hybrid & Inorgan Mat GQMATHI, Sao Carlos, SP - Brazil
[3] Univ Tecnol Fed Parana, Polymers & Nanostruct Res Grp GPAN, Toledo - Brazil
[4] Nascimento, Matheus, V, Fraunhofer Inst Mfg Technol & Adv Mat IFAM, Bremen - Germany
[5] Fed Univ Rio Grande do Sul Labsinal UFRGS, Porto Alegre, RS - Brazil
Total Affiliations: 5
|
| Document type: | Journal article |
| Source: | Applied Surface Science; v. 484, p. 1128-1140, AUG 1 2019. |
| Web of Science Citations: | 1 |
| Abstract | |
In this study, we propose new polymeric coatings for metallic implants that impart biocompatibility and antibacterial features to such surfaces. The starting material, poly(cyclic carbonate)-polydimethylsiloxane, was prepared from carbon dioxide fixation and then sequentially reacted by aminolysis with an organoaminosilane, affording the formation of an urethanic polydimethylsiloxane-based material. Finally, a hybrid coating was obtained by performing a sol-gel process on the metallic surfaces, catalyzed by phosphotungstic acid. We provide evidence that due to the polydimethylsiloxane segments governing the surface termination, the hybrid coatings show a hydrophobic character. Furthermore, due the presence of phosphotungstic acid in the upper surface, the adhesion of Gram-positive and Gram-negative bacteria is suppressed in 4 h of contact with aqueous bacterial cultures. In addition, the coatings presented a > 70% cytocompatibility besides a low cytotoxicity, making them interesting candidates as biocompatible materials and an alternative to avoiding the biofilm associated with bacterial infections. (AU) | |
| FAPESP's process: | 13/05279-3 - Poly(dimethylsiloxane) based segmented urethanes biomimetic adhesives Based on CO2 fixation |
| Grantee: | Kelen Menezes Flores Rossi de Aguiar |
| Support Opportunities: | Scholarships abroad - Research Internship - Doctorate |
| FAPESP's process: | 11/08120-0 - Nanostructured films: on the influence of the architecture on Photoactivity properties of films with phosphotungstate and nanoparticles |
| Grantee: | Ubirajara Pereira Rodrigues Filho |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 11/06019-0 - CO2 uptake and synthesis of polyuretanes-polysilicone co-polymers as additives incorporated in ormosils: use on bioactive and ion conducting films |
| Grantee: | Kelen Menezes Flores Rossi de Aguiar |
| Support Opportunities: | Scholarships in Brazil - Doctorate |