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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Which Variables Matter for Process Design and Scale-Up? A Study of Sugar Cane Straw Pretreatment Using Low-Cost and Easily Synthesizable Ionic Liquids

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Ferrari, Felipe Augusto [1, 2] ; Brandao Pereira, Jorge Fernando [3] ; Witkamp, Geert-Jan [4] ; Soares Forte, Marcus Bruno [1]
Total Authors: 4
[1] Univ Campinas UNICAMP, Fac Food Engn, Dept Food Engn, Bioproc & Metab Engn Lab, Monteiro Lobato St 80, BR-13083862 Campinas, SP - Brazil
[2] Technol Univ Delft TUDelft, Fac Appl Sci, Biotechnol Dept, Bioproc Engn Sect, NL-2629 HZ Delft - Netherlands
[3] Sao Paulo State Univ UNESP, Sch Pharmaceut Sci, Dept Bioproc & Biotechnol, Rodovia Araraquara Jau, Km 01, BR-14800903 Araraquara, SP - Brazil
[4] KAUST, Water Desalinat & Reuse Ctr WDRC, Div Biol & Environm Sci & Engn BESE, Thuwal 239556900 - Saudi Arabia
Total Affiliations: 4
Document type: Journal article
Source: ACS SUSTAINABLE CHEMISTRY & ENGINEERING; v. 7, n. 15, p. 12779-12788, AUG 5 2019.
Web of Science Citations: 0

Ionic liquids (ILs) have great potential as solvents and catalysts for pretreatment of lignocellulosic biomass. However, process scale-up necessitates that IL-based pretreatment methods be optimized in terms of cost and sustainability. In this study, low-cost and easily synthesizable ethanolammonium-based ILs were prepared and used in the pretreatment of sugar cane straw (SW). The effects of ILs, IL mixtures, pretreatment temperature, water content, solids loading, ultrasonication, and agitation speed on residual solids enzymatic digestibility and delignification were systematically assessed, and the process was scaled up from a 50 mL static flask to a 1 L impelled reactor. IL mixtures improved enzymatic digestibility at higher solids loading and water addition in the reaction medium under mild temperature conditions (90 degrees C). Enzymatic hydrolysis of residual solids after bench-scale pretreatment of SW for 3 h at 15% (w/w) solids loading and 20% (w/w) water content in the liquid phase resulted in 98% cellulose digestibility under nonoptimized conditions. This study provides a practical review of IL-based pretreatment methods, discusses the selection of variables for process design and scale-up, and presents empirical results. (AU)

FAPESP's process: 14/16424-7 - Optimization and scale-up of liquid-liquid extraction process with ionic liquids (ILs) as a sustainable tool for the separation of the anti-leukemia biopharmaceutical L-asparaginase (ASPase)
Grantee:Jorge Pereira
Support Opportunities: Research Grants - Young Investigators Grants
FAPESP's process: 15/50612-8 - An integrated approach to explore a novel paradigm for biofuel production from lignocellulosic feedstocks
Grantee:Telma Teixeira Franco
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 17/24520-4 - New generation biofuel and feedstock pre-treatment challenge: a novel strategy to assess biomass processing using mixtures of ionic liquids and ultrasound, a simultaneous and multivariate approach
Grantee:Marcus Bruno Soares Forte
Support Opportunities: Program for Research on Bioenergy (BIOEN) - Regular Program Grants