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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Prevalence of hepatitis E virus infection in multiple transfused Brazilian patients with thalassemia and sickle cell disease

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Author(s):
Slavov, Svetoslav N. [1, 2] ; Maconetto, Juliana D. M. [2] ; Martinez, Edson Z. [3] ; Silva-Pinto, Ana Cristina [2] ; Covas, Dimas T. [4, 2] ; Eis-Huebinger, Anna Maria [5] ; Kashima, Simone [2]
Total Authors: 7
Affiliation:
[1] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Internal Med, Ribeirao Preto, SP - Brazil
[2] Univ Sao Paulo, Fac Med Ribeirao Preto, Blood Ctr Ribeirao Preto, Lab Mol Biol, 2501 Tenente Catao Roxo St, BR-14051140 Ribeirao Preto, SP - Brazil
[3] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Social Med, Ribeirao Preto, SP - Brazil
[4] Butantan Inst, Sao Paulo - Brazil
[5] Univ Bonn, Inst Virol, Med Ctr, Bonn - Germany
Total Affiliations: 5
Document type: Journal article
Source: Journal of Medical Virology; v. 91, n. 9, p. 1693-1697, SEP 2019.
Web of Science Citations: 0
Abstract

Hepatitis E virus (HEV) is a leading cause of acute hepatitis worldwide. The virus is acquired by fecal-oral route; however, it can also be transmitted by blood transfusion. The objective of the study was to examine anti-HEV immunoglobulin G and HEV RNA prevalence in multiple transfused patients with thalassemia and sickle cell disease (SCD), and in blood donors. The HEV seroprevalence in the patients was 13% (20% in thalassemics; 7.7% in SCD), and 11% in blood donors. No positive result for HEV RNA was obtained. This is a pioneer study examining HEV circulation in Brazilian patients with hemoglobinopathies. (AU)

FAPESP's process: 09/16623-1 - Molecular pathogenesis and clinical consequences of the infections caused by the Human Parvovirus B19 and Human Cytomegalovirus among patients with hemaglobinopathies and haemophilia
Grantee:Svetoslav Nanev Slavov
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 17/23205-8 - Evaluation of the impact of emerging and reemerging viruses in the field of hemotherapy and stem cell transplantation by multiple-research approach
Grantee:Svetoslav Nanev Slavov
Support Opportunities: Research Grants - Young Investigators Grants
FAPESP's process: 14/50947-7 - INCT 2014: in Stem Cell and Cell Therapy
Grantee:Dimas Tadeu Covas
Support Opportunities: Research Projects - Thematic Grants