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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Long-term nanomechanical properties and gelatinolytic activity of titanium tetrafluoride-treated adhesive dentin interface

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Author(s):
Bridi, Enrico Coser [1] ; Leme-Kraus, Ariene Arcas [2] ; Basting, Roberta Tarkany [1] ; Bedran-Russo, Ana Karina [2]
Total Authors: 4
Affiliation:
[1] Sao Leopoldo Mand Inst & Dent Res Ctr, Rua Jose Rocha Junqueira 13, BR-13045755 Campinas, SP - Brazil
[2] Univ Illinois, Coll Dent, Dept Restorat Dent, 801 South Paulina St, Chicago, IL 60612 - USA
Total Affiliations: 2
Document type: Journal article
Source: Dental Materials; v. 35, n. 10, p. 1471-1478, OCT 2019.
Web of Science Citations: 0
Abstract

Objective. This study investigated the effects of dentin pretreatment with 2.5% titanium tetrafluoride ( TiF4) on nanomechanical properties, and the in situ gelatinolytic activity of the dentin-resin interface, for up to 6 months. Methods. Twenty-four human teeth were prepared by exposing occlusal flat dentin surfaces, and were randomly assigned to experimental groups, according to application or non-application of a TiF4 pretreatment, and to the adhesive systems (Clearfil SE Bond or Scotchbond Universal). Resin composite (Filtek Supreme Ultra) was built up incrementally on the teeth in all the groups. Then, the specimens were sectioned and randomly selected for evaluation at 24 h, 3 months and 6 months of storage time. The reduced modulus of elasticity (E-r) and the nanohardness of the underlying dentin, as well as the hybrid layer and the adhesive layer were measured using a nanoindenter. Gelatinolytic activity at the dentin-resin interfaces was assessed by in situ zymography using quenched fluorescein-conjugated gelatin at 24 h and 6 months. Statistical analyses were performed with ANOVA and Tukey's tests. Results. There were no differences in E-r and nanohardness values between adhesives systems and pretreatment (p = 0.1250). In situ zymography showed significantly higher gelatinolytic activity after 6 months for all the experimental groups (p = 0.0004), but no differences between the adhesive systems (p = 0.7708) and the surface pretreatment (p = 0.4877). Significance: Dentin pretreatment with 2.5% TiF4 followed by self-etching adhesive systems did not influence nanomechanical properties or gelatinolytic activity of the adhesive-dentin interface layers, over time. (C) 2019 The Academy of Dental Materials. Published by Elsevier Inc. All rights reserved. (AU)

FAPESP's process: 14/18848-9 - Long-term evaluation of the stability of dentin matrix following treatment with titanium tetrafluoride and the nano-mechanical properties of the dentin-adhesive interface
Grantee:Enrico Coser Bridi
Support Opportunities: Scholarships abroad - Research Internship - Doctorate