Natural products involved in the symbiosis between Amycolatopsis and attine ants
| Full text | |
| Author(s): |
dos Reis, Gislaine Vicente
[1]
;
Abraham, Wolf-Rainer
[2]
;
Grigoletto, Diana Fortkamp
[1, 2]
;
de Campos, Jessica Bueno
[3]
;
Marcon, Joelma
[3]
;
da Silva, Jose Antonio
[3]
;
Quecine, Maria Carolina
[3]
;
de Azevedo, Joao Lucio
[3]
;
Ferreira, Antonio Gilberto
[4]
;
de Lira, Simone Possedente
[1]
Total Authors: 10
|
| Affiliation: | [1] Univ Sao Paulo, Dept Exact Sci, Coll Agr Luiz de Queiroz, BR-13418900 Piracicaba, SP - Brazil
[2] Helmholtz Ctr Infect Res, Chem Microbiol, D-38124 Braunschweig - Germany
[3] Univ Sao Paulo, Dept Genet, Coll Agr Luiz de Queiroz, BR-13418900 Piracicaba, SP - Brazil
[4] Univ Fed Sao Carlos, Dept Chem, BR-13565905 Sao Carlos, SP - Brazil
Total Affiliations: 4
|
| Document type: | Journal article |
| Source: | FEMS Microbiology Letters; v. 366, n. 14 JUL 2019. |
| Web of Science Citations: | 0 |
| Abstract | |
Actinobacteria are known by their ability to produce several antimicrobial compounds of biotechnological interest. Thus, in this study, we isolated and identified by partial 16S RNA sequencing similar to 100 actinobacteria isolates from guarana (Paullinia cupana) bulk soil. Besides, we isolated from the actinobacteria Streptomyces morookaense AM25 a novel cyclic peptide, named gloeosporiocide, molecular formula C44H48N11O7S3 (calculated 938.2901), and characterized by the presence of cyclized cysteins to form three thiazols. The novel compound had activity against the plant pathogen Colletotrichum gloeosporioides, assayed by the paper disk diffusion method (42.7% inhibition, 0.1 mg disk(-1)) and by the microdilution assay (1.25 g L-1). Our results reveal the potential of the actinobacteria from the Amazon rhizospheric soils as biocontrol agents as well as producers of new compounds with antifungal activity. Thus, this work constitutes a step forward in the development of the biotechnology of actinobacteria in the production of compounds of agronomic interest. (AU) | |
| FAPESP's process: | 13/50228-8 - Biodiversity components, and its metabolic characters, of Brazilian Islands |
| Grantee: | Roberto Gomes de Souza Berlinck |
| Support type: | BIOTA-FAPESP Program - Thematic Grants |
| FAPESP's process: | 14/15760-3 - Biotechnological potential of secondary metabolites from plants and endophytic fungi |
| Grantee: | Simone Possedente de Lira |
| Support type: | Regular Research Grants |