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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Frailty and cognitive performance in older adults living in the community: a cross-sectional study

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Author(s):
DAIENE DE MORAIS FABRÍCIO [1] ; TIAGO DA SILVA ALEXANDRE [2] ; MARCOS HORTES NISIHARA CHAGAS
Total Authors: 3
Affiliation:
[1] Federal University of São Carlos. Department of Psychology - Brasil
[2] Federal University of São Carlos. Department of Gerontology - Brasil
Total Affiliations: 3
Document type: Journal article
Source: ARCHIVES OF CLINICAL PSYCHIATRY; v. 46, n. 6, p. 151-155, 2019-11-28.
Abstract

Abstract Background Cognitive impairment and frailty are important problems affecting the elderly population. Frail elderly present worse overall cognitive performance. Objective The aim of this study was to investigate general and domain-specific cognitive performance among non-frail, pre-frail, and frail elderly persons. Methods This is a cross-sectional study in which 267 elderly persons living in São Carlos, SP were divided into three groups according to the frailty criteria defined by Fried et al. Cognitive performance was evaluated with a battery of cognitive tests covering domains such as memory, attention, language, and executive functioning. A multinomial logistic regression analysis adjusted for age, gender, and education was performed to evaluate the association between performance in cognitive domains and levels of frailty. Results Frailty was significantly associated with lower scores on the global cognitive test (RRR = 0.86; IC 95% 0.78-0.96; p < 0.01), word list memory (RRR = 0.92; IC 95% 0.86-0.99; p = 0.02), and figure list recognition (RRR = 0.78; IC 95% 0.62-0.99; p = 0.04). Pre-frailty was associated with lower scores on the word list memory (RRR = 0.92; IC 95% 0.86-1.00; p = 0.04) and naming test (RRR = 0.82; IC 95% 0.69-0.99; p = 0.03). Discussion Frailty syndrome can influence general cognition and specific domains such as memory and language. Prospective studies will be fundamental to evaluate the causal relation between frailty and cognition. (AU)

FAPESP's process: 15/16412-1 - Social cognition and comparison of DSM-IV and DSM-5 dementia criteria among elderly attended in primary care
Grantee:Marcos Hortes Nisihara Chagas
Support Opportunities: Regular Research Grants